[bioundgrd] FW: Research assistant position Schaffer lab

Joshua Stone stonej at mit.edu
Fri Mar 29 11:57:29 EDT 2019


From: "Schaffer, Jean" <jschaff at wustl.edu<mailto:jschaff at wustl.edu>>


Research Assistant Job
Schaffer Lab at Joslin Diabetes Center and Harvard Medical School

The Schaffer lab studies diabetes and its cardiovascular complications. We are using genetic, biochemical, cell biological, and physiological approaches to elucidate mechanisms through which abnormally high levels of metabolites cause cell dysfunction and cell death. Current areas of focus include non-canonical functions of small nucleolar RNAs (snoRNAs), regulated RNA degradation, and translational regulation in response to metabolic stress. Other areas of interest are post-lysosomal cholesterol trafficking networks and disruption of these pathway in disorders of cholesterol metabolism. Our goal is to discover fundamental mechanisms of metabolic stress responses and to translate our findings in ways that inform development of approaches to improve the lives of patients with metabolic diseases.

Our laboratory is moving to the Joslin Diabetes Center at Harvard Medical School in July 2019. An opening is available for a graduate with an interest in basic and translational studies with high relevance to important human diseases. This position will afford the opportunity to learn a broad array of techniques and gain first-hand experience in design, execution and interpretation of experiments. Previous graduates who have worked during gap years in our laboratory have earned authorship on publications and have gone on to succeed in MD/PhD, MD, and PhD programs.

Ideal candidates will be curious, highly motivated, responsible, and self-directed learners. They should have a strong background in molecular cell biology and chemistry and prior laboratory experience. Applicants must be willing to commit for a minimum of two years of work.

For more information on our lab and interests, visit https://schafferlab.wustl.edu
To apply, email a resume and cover letter to Jean Schaffer, MD (jschaff at wustl.edu)<mailto:jschaff at wustl.edu)>



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