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<p class="MsoNormal"><b><span style="font-family:"-webkit-standard",serif;color:black">From: </span></b><span style="font-family:"-webkit-standard",serif;color:black">"Schaffer, Jean" <<a href="mailto:jschaff@wustl.edu">jschaff@wustl.edu</a>><o:p></o:p></span></p>
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<p class="MsoNormal" align="center" style="text-align:center"><b>Research Assistant Job</b><b><span style="font-family:"Arial",sans-serif"><o:p></o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b>Schaffer Lab at Joslin Diabetes Center and Harvard Medical School<o:p></o:p></b></p>
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<p class="MsoNormal" style="text-align:justify">The Schaffer lab studies diabetes and its cardiovascular complications. We are using genetic, biochemical, cell biological, and physiological approaches to elucidate mechanisms through which abnormally high levels
of metabolites cause cell dysfunction and cell death. Current areas of focus include non-canonical functions of small nucleolar RNAs (snoRNAs), regulated RNA degradation, and translational regulation in response to metabolic stress. Other areas of interest
are post-lysosomal cholesterol trafficking networks and disruption of these pathway in disorders of cholesterol metabolism.
<span class="s1"><span style="color:black">Our goal is to discover fundamental mechanisms of metabolic stress responses and to translate our findings in ways that inform development of approaches to improve the lives of patients with metabolic diseases.
<o:p></o:p></span></span></p>
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<p class="MsoNormal" style="text-align:justify"><span class="s1"><span style="color:black">Our laboratory is moving to the Joslin Diabetes Center at Harvard Medical School in July 2019. An opening is available for a graduate with an interest in basic and translational
studies with high relevance to important human diseases. This position will afford the opportunity to learn a broad array of techniques and gain first-hand experience in design, execution and interpretation of experiments.
</span></span>Previous graduates who have worked during gap years in our laboratory
<span class="s1"><span style="color:black">have earned authorship on publications and have gone on to succeed in MD/PhD, MD, and PhD programs.</span><o:p></o:p></span></p>
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<p class="MsoNormal" style="text-align:justify"><span class="s1"><span style="color:black">Ideal candidates will be curious, highly motivated, responsible, and self-directed learners. They should have a strong background in molecular cell biology and chemistry
and prior laboratory experience. Applicants must be willing to commit for a minimum of two years of work.<o:p></o:p></span></span></p>
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<p class="MsoNormal" style="text-align:justify"><span class="s1"><span style="color:black">For more information on our lab and interests, visit https://schafferlab.wustl.edu</span></span><span class="s1"><span style="color:black"><o:p></o:p></span></span></p>
<p class="MsoNormal" style="text-align:justify">To apply, email a resume and cover letter to Jean Schaffer, MD (<a href="mailto:jschaff@wustl.edu)">jschaff@wustl.edu)</a><o:p></o:p></p>
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