[bioundgrd] Fwd: IAP Research Position at Takeda Pharmaceuticals

[Janice Chang]

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Subject: IAP Research Position at Takeda Pharmaceuticals
Date: November 25, 2014 at 2:25:17 AM EST



Do you aspire to solve problems in cancer?

Interested in computational biology research and exploring industry?

The Modeling and Simulation group at Takeda Pharmaceuticals in Cambridge, MA is looking for Research Affiliates to work on modeling projects investigating evolution in tumors and its impact on treatment success.


Who we are

We are a fast-moving group whose mission is to support rational quantitative decision-making in drug discovery and development through the application of mathematical modeling.  In particular, we identify ways to translate preclinical data into recommendations for clinical development, and to make drugs more developable at every step along the way. We take a forward-thinking approach and build novel capabilities through focused research projects applying mathematical modeling to drug development in new ways.


What you will do

As a research affiliate, you will work on an independent project in theoretical cancer biology. Working closely with our scientists, you will explore in-depth an industry-relevant basic science question with the goal of producing your own academic publication. This opportunity will give you research experience in support of a career in scientific positions in academia or industry.


Potential projects will involve using modeling and simulation to investigate the evolutionary process in tumors including the impact of tumor heterogeneity on disease progression, and how treatment affects the evolutionary dynamics of a cancer. Projects are expected to take a total of 150 hours to complete, and you should plan on committing at least 20 hours per week during January followed by 8-10 hours per week from February through March. All work is theoretical or computational, and does not require any wet-lab components.


Who you are

•         Current graduate or undergraduate student, or post-doc. All majors and years welcome.
•         Experience with mathematical modeling, differential equations, and statistics.
•         Proficiency with MATLAB, Mathematica, R, Python, or similar.
•         Exposure to evolutionary dynamics and/or game theory is a plus.
•         Comfortable with reading and analyzing scientific literature.
•         Experience with publications is a plus.
•         Organized, with an ability to prioritize time-sensitive assignments.
•         Motivation and creativity to solve problems in cancer biology.


Details

•         $17/hr (20 hours per week during January 2015, followed by 8-10 hours per week through March 2015 for approximately 150 hours total.)
•         Publication expected (minimally, an abstract at an international conference; potential for publication in a peer-reviewed journal.)



How to Apply


Contact Christopher.Zopf at takeda.com<mailto:Christopher.Zopf at takeda.com> with your resume by December 3, 2014.



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