[Sci-tech-public] Victor McElheny talk on the Genome Nov. 1
David Mindell
mindell at MIT.EDU
Sun Oct 17 21:01:13 EDT 2010
Please join us November 1 for a talk by our friend and colleague Victor
McElheny:
Genomic History: Open Items
DATE: Monday, November 1
TIME: 4:30pm-6:30pm
ROOM: E51-149
An abstract from Victor:
Just finishing a survey of the history of the 20-year-old Human
Genome Project and its immediate results (Drawing the Map of Life,
Basic Books, 2010) makes me acutely conscious of the large number of
unanswered or partly answered questions relating to this immense and
still unfolding aspect of contemporary biology. Several of these
concern the origins of what many thought was an improbable enterprise:
1) the relative influence of technical advances, 2) discoveries of
gene-related diseases, 3) the political experience of the "War on
Cancer" and the recombinant DNA controversy in the 1970s, 4) the
difficulty in measuring environmental sources of cancer, and 5) the
desire to demonstrate the medical utility of molecular biology. Among
other open items: 1) the technologically conservative choice to use
existing DNA sequencing technology for the big push to the first
complete human sequence; 2) detailed management of the global non-
profit human genome consortium, evidenced in multi-time-zone Friday
teleconferences of which extensive notes exist; 3) the technical
evolution of the profusion of competing "next generation" sequencing
machines that are bringing the day of $1,000 human genomes very close;
4) the influence of ethical concerns on the course of the project; and
5) controversy over the relative role of rare or common variants in
increasing or decreasing an individual's risks of disease. All this
points to the need, in the fairly near future, of a comprehensive
history of genomics, probably by multiple authors. Could this be ready
by the 25th anniversary of the project in 2015?
Speaker. Victor McElheny, a science journalist since 1957, was
founding director of STS' daughter program, the Knight Science
Journalism Fellowships, from 1982 to 1998, when he became an STS
Visiting Scholar. Since then, he as published three books, Insisting
on the Impossible, The Life of Edwin Land, Inventor of Instant
Photography (Perseus, 1998); Watson and DNA: Making a Scientific
Revolution (Perseus 2003); and Drawing the Map of Life: Inside the
Human Genome Project (Basic Books, 2010). Earlier he was a staff
reporter for the Charlotte (NC) Observer, Science magazine, the Boston
Globe, and the New York Times, covering such topics as science in
Antarctica, the nuclear energy program of India, the Apollo lunar
landing program, and, starting in 1960, advances in biological
science. In 1978-82, he was the first director of the Banbury Center
of Cold Spring Harbor Laboratory.
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