[CSBi-events] MicroArray Club meeting

[csbi-events@mit.edu]

MIT BioMicro Center MicroArray Club
A  monthly meeting on methods, results and instruments

Wednesday  June 8th, 2005

Title :      " SpliceArray: A new generation of microarray that enables 
rapid detection of alternative splicing events "

Speaker:   Richard Einstein, Ph.D.
                 Vice President Research
                 ExonHit Therapeutics Inc.

Venue:    Rm 68-121, 4 PM


Abstract:
The maturation of microarray technology over the past ten years has allowed 
the research community to begin to decipher the complex relationship 
between gene expression and physiological function.  By employing a novel 
patented array design that monitors the expression of alternatively spliced 
exons and junctions, ExonHit Therapeutics' SpliceArrays now empower 
scientists to investigate and discover disease-associated isoforms at a 
level previously unattainable by microarrays.

These observations add an exciting new level of complexity not typically 
considered and also add great potential for the discovery of novel 
therapeutic targets.  This seminar will discuss SpliceArray content, probe 
design, data analysis, validation studies and discussion of currently 
available SpliceArrays (GPCRs,  Ion Channels,  Nuclear Receptors and 
Apoptosis)).  Possible applications of this technology in your current 
research and the development of custom SpliceArrays will also be 
addressed.  A question and answer session will follow the presentation.


P.S. Refreshments will be provided.



Organizers:

Noam Shomron (nshomron at mit.edu)
Sanchita Bhattacharya (sanchita at mit.edu)


Dawn Davis Loring
Communications Coordinator
Computational and Systems Biology (CSBi)
Phone: (617) 324-0150
Fax: (617) 324-0081

Massachusetts Institute of Technology
77 Massachusetts Avenue
Building 68 - Room 459
Cambridge, MA 02139