[Crib-list] SPEAKER: MALA L. RADHAKRISHNAN -- Computational Research in Boston Seminar -- Friday, March 7, 2008 -- 12:30 PM == Room 32-144 (Stata)

[Shirley Entzminger]

 			COMPUTATIONAL RESEARCH in BOSTON SEMINAR


Date:		FRIDAY, MARCH 7, 2008
Time:		12:30 PM
Location:	Building 32, Room 144  (STATA CENTER)

(Pizza and beverages will be provided at 12:15 PM.)


Title:		COMPUTATIONAL DRUG DESIGN AND ANALYSIS:
 		A MULTIFACETED APPROACH


Speaker:	MALA L. RADHAKRISHNAN  (Wellesley College)


ABSTRACT:

Computation is playing an increasingly significant role in the design and 
analysis of drug molecules to treat disease.  Using the HIV-1 protease 
system and other systems as case studies, I will address the many ways in 
which computation can specifically tackle system-specific challenges such 
as drug resistance and drug degradation.  Theory, physics-based models, 
optimization methods, and phenomological larger-scale models can all be 
integrated into a multi-facted approach to better understand the action of 
current drugs and to design novel ones for the future.

*****************************************************************************

Massachusetts Institute of Technology
Cambridge, MA  02139


http://www-math. mit.edu/crib

For information on CRiB, contact:

Alan Edelman:  edelman at math.mit.edu
Steven G. Johnson:  stevenj at math.mit.edu
Jeremy Kepner:  kepner at ll.mit.edu
Patrick Dreher:  dreher at mit.edu