[bioundgrd] Biology UROP opportunity available

[Janice Chang]

Biology UROP opportunity availalbe in Prof. Terry Orr-Weaver's lab. 
Please contact her at weaver at wi.mit.edu if you are interested.

>Developmental Regulation of DNA Replication
>Proper regulation of the initiation of DNA replication is essential 
>to maintain accurate genomic content, and defects in replication 
>leading to increases or decreases in gene copy number are one cause 
>of cancer.  A limitation to identifying regulatory mechanisms for 
>replication initiation in higher eukaryotes has been the difficulty 
>in isolating replication origins.  This project will exploit model 
>replicons identified in Drosophila to define control mechanisms for 
>replication initiation.  Both genetic and cell biology approaches 
>will be used to monitor DNA replication in transgenic lines.
>
>Completion of 7.02 and 7.03 are required.


Regards,
Janice

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