[bioundgrd] Biology UROP opportunity available
Janice Chang
jdchang at MIT.EDU
Wed Mar 11 10:28:03 EDT 2009
Biology UROP opportunity availalbe in Prof. Terry Orr-Weaver's lab.
Please contact her at weaver at wi.mit.edu if you are interested.
>Developmental Regulation of DNA Replication
>Proper regulation of the initiation of DNA replication is essential
>to maintain accurate genomic content, and defects in replication
>leading to increases or decreases in gene copy number are one cause
>of cancer. A limitation to identifying regulatory mechanisms for
>replication initiation in higher eukaryotes has been the difficulty
>in isolating replication origins. This project will exploit model
>replicons identified in Drosophila to define control mechanisms for
>replication initiation. Both genetic and cell biology approaches
>will be used to monitor DNA replication in transgenic lines.
>
>Completion of 7.02 and 7.03 are required.
Regards,
Janice
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