[bioundgrd] BMES Distinguished Lecture Series

[Janice Chang]

>From:
>Chensi Ouyang
>
>I am the co-Vice President of Special Programs 
>in the Bio-medical Engineering Society.  BMES 
>will be hosting a lecture on October 12 as part 
>of our monthly Distinguished Lecture Series. 
>The speaker is Dr. Can Ozbal, who used to be a 
>graduate student at MIT and now is a program 
>manager at BioTrove Inc.  He will be speaking 
>about the development of RapidFire (tm) MS 
>interface for mass spectroscopy.
>
>--------------------------------------------------------
>
>The Biomedical Engineering Society (BMES) 
>invites you to attend our Distinguished Lecture 
>Series on October 12th, with Dr. Ozbal of 
>Biotrove, Inc. as our distinguished speaker.
>
>************************************************
>Wednesday. October 12, 2005.
>Refreshments at 6:30 pm.
>Lecture at 7:00 pm.
>Room 66-110.
>------------------------------------------------
>
>High-Throughput Mass Spectrometry: From Concept to Commercialization
>
>Can C. Özbal, Ph.D.
>Program Manager, RapidFire" Lead Discovery
>BioTrove Inc.
>
>------------------------------------------------
>
>Mass spectrometry (MS) is a powerful analytical 
>tool that has the ability to quantify selected 
>analytes based on molecular weight.  As such, MS 
>has become a widely used tool in many phases of 
>drug development, ranging from target discovery 
>and validation through lead optimization and 
>biomarker discovery.  One limitation of the use 
>of mass spectrometry is the incompatibility of 
>the method with samples that contain 
>non-volatile components, such as salts and 
>buffers, due to ion suppression and 
>precipitation in the MS ion source.  Analysis of 
>such samples requires an initial chromatography 
>step that is typically the rate-limiting factor 
>on MS throughput.  BioTrove has developed the 
>RapidFireTM MS interface that enables sustained 
>throughputs of MS systems at 4 to 8 seconds per 
>sample, enabling the use of mass spectrometry in 
>primary screening for lead compound 
>identification.  The talk will focus on the 
>technology and its commercialization. 
>
>After receiving an A.B. in chemistry with honors 
>from Bowdoin College, Dr. Ozbal joined the 
>laboratory of Steven Tannenbaum at M.I.T. where 
>he earned his Ph.D. in Toxicology.  His doctoral 
>work involved the quantification of DNA and 
>protein adducts of a class of environmental 
>carcinogens known as polycyclic aromatic 
>hydrocarbons and required the development of new 
>instrumentation and ultra-sensitive analytical 
>methods.  After graduation Dr. Özbal stayed on 
>at M.I.T. as an instructor where he was involved 
>in the teaching of undergraduate level lecture 
>and laboratory courses.  Dr. Özbal left M.I.T. 
>to join BioTrove as one of its first employees 
>where he was responsible for much of the 
>RapidFire technology development, including the 
>ultra high throughput mass spectrometry 
>interface.  Currently he is the manager of the 
>RapidFire business unit at BioTrove and is 
>involved in both commercial and scientific 
>operations.
>
>
>************************************************
>co-sponsored by the IEEE EMBS, Boston Chapter.
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