[MOS] 9/24 - Modern Optics and Spectroscopy Seminar with Haw Yang (Princeton University)

[Christine Brooks]

There will be a Modern Optics and Spectroscopy Seminar held next Tuesday, September 24 in 34-401A<http://whereis.mit.edu/?go=34>

Haw Yang
Princeton University

“Real-Time 3D Single-Particle Tracking: Spectroscopy, Imaging, and Control”

Real-time 3D single-particle tracking spectroscopy (RT-3DSPT) is an experimental technique that allows one to follow a nanoscale probe, or a single molecule in special circumstances, as it moves in three-dimensional space. The probe’s movement could be diffusive or active locomotion. The technique keeps the nano-probe at the center of a microscope objective focus at all times by moving the sample stage to counter any movements that the probe exhibits. Effectively, the apparatus transforms the experimental coordinate from a lab-based frame to a probe-based frame. This way, it becomes possible to do time-dependent experiments on the probe, or on the molecule tethered to the probe, as if the particle or the molecule is immobilized. This unconventional experimental approach could enable many interesting research avenues that are not possible before. This presentation will discuss its principle, capabilities and current limitations, as well as new research directions in my laboratory based on RT-3DSPT—including (1) single-particle spectroscopy, (2) 3D multi-resolution imaging and its application to individual virus-like nanoparticles interacting with a live cell (nano-bio interactions), and (3) steering of self-propelled micro-swimmers.


Refreshments will be served immediately following the seminar!


Christine Brooks
Administrative Assistant
Massachusetts Institute of Technology
Department of Chemistry
77 Massachusetts Ave, 6-333
Cambridge, MA 02139
p: 617.253.7239
e: cbrooks at mit.edu<mailto:cbrooks at mit.edu>

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