[MOS] Tuesday, March 9, 2004; Joseph Izatt, Duke University

[Vinnie Russo]

Dear Colleagues,

The G.R. Harrison Spectroscopy Laboratory and the Department of Electrical 
Engineering and Computer Science would like to invite you to the next 
seminar in our series on Modern Optics and Spectroscopy.

Date & Time:            Tuesday, March 9; 12 noon  1 PM

Location:               Grier Room (34-401)

Speaker:                Joseph Izatt, Duke University

Title:          Novel System Designs and Molecular Contrast in Optical 
Coherence Tomography

Refreshments will be served following the talk.


Abstract:

Joseph Izatt, Duke University
Novel System Designs and Molecular Contrast in Optical Coherence Tomography
Optical Coherence Tomography (OCT) is a novel biomedical imaging technique 
which uses low-coherence optical interferometry to obtain micron-scale 
resolution tomographic images of sub-surface tissue structure 
noninvasively. We have developed OCT scanners compatible with minimally 
invasive delivery technologies (i.e., biomicroscopy, endoscopy) capable of 
imaging up to video rate. Clinical studies of OCT imaging in the eye, skin, 
and gastrointestinal tissues are under way which demonstrate reproducible 
image contrast between morphological tissue layers, as well as 
differentiation between normal and abnormal tissue regions. We have also 
demonstrated OCT applications for noninvasive 3D imaging in embryos and 
small animals. We report on dramatic recent technical advances in OCT which 
have significantly enhanced its capability for minimally invasive clinical 
diagnostics and for basic biological research. These include system designs 
which achieve a significant SNR advantage through parallel detection, as 
well as the first demonstrations of molecular imaging with OCT.



Vinnie Russo * vrusso at mit.edu  *  Office Manager
MIT; G.R. Harrison  Spectroscopy Laboratory
77 Mass. Ave., 6-014  *  Cambridge, MA  02139
(v) 617-253-9774  *  (f) 617-253-4513
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