Job posting - Director of iPS Core Lab Facility, Duke Univ.

[Debra L. Martin]

The Duke University School of Medicine invites applications for the 
position of Director of a newly created iPS Core Laboratory Facility. 
This facility will play a key role in supporting Duke's efforts to 
advance the field of stem cell research through the development and 
application of reprogramming technologies using induced pluripotent 
stem (iPS) cells. 

The iPS Core will provide Duke researchers with training and access 
to cutting edge capabilities to support their own research endeavors, 
with a focus on the derivation and storage of new iPS cell lines. 
The Core will serve as a repository for iPS cells produced by Duke 
investigators and a laboratory for the generation and 
characterization of new disease-specific lines.  The Director will 
oversee the scientific output of the Core through the day-to-day 
management of operations, personnel and finances.  The Director will 
ensure that exceptional support is provided to the Duke research 
community in a timely, economical, and regulatory compliant manner. 
In addition, the iPS Core will contribute to the efforts of the 
broader research community through the large scale production and 
global distribution of iPS cell lines developed by Duke scientists. 

The Director will report to Brigid Hogan, Ph.D., Professor and Chair, 
Department of Cell Biology.  Dr. Hogan will lead a faculty governance 
board for the Core.

Responsibilities:  This role will include the following specific 
responsibilities:

o	Provide scientific and technical expertise necessary to 
assist researchers in designing the experimental framework for their 
investigations.  Foster a collaborative process for the design of all 
iPS cell experiments via discussions between senior laboratory staff 
and the investigators utilizing the Core resources.  Ensure that 
research staff have a clear understanding of the desired metrics of 
success for each experiment and that scientists are fully informed of 
laboratory procedures, requirements and costs.

o	Oversee laboratory facilities including space, equipment and 
supplies.  Facilitate the selection, procurement, and maintenance of 
equipment.  Ensure adherence to environmental requirements.  Develop 
and implement processes for scheduling and training of new users.

o	Oversee laboratory operations including the development and 
maintenance of standard operating procedures for cell culture and 
other specialized laboratory techniques as well as quality control 
and assurance activities.  Manage cell culture procedures through 
established protocols, and design and evaluate protocols for new 
technical services.  Foster effective project and resource management 
needed for successful operations and service.

o	Identify opportunities to leverage information technology to 
facilitate the efficient operation of the Core and made 
recommendations regarding the purchase of hardware and software, 
application development, etc.

o	Develop and manage the Core's annual operating budget and 
cost recovery mechanism to ensure long-term financial sustainability. 

o	Identify strategies for improving and enhancing the Core's 
services to the research community and make recommendations to 
leadership regarding opportunities to develop and implement new 
resources and capabilities.

o	Maintain a strong awareness of other shared resources at Duke 
that may be of benefit to investigators involved in iPS cell research 
and facilitate connections as appropriate.

o	Identify and implement opportunities to inform prospective 
Core users of the capabilities, expertise and services available.

Qualifications:

Candidates must hold a PhD in cell biology, or related field, with a 
focus on molecular biology or developmental and stem cell biology, as 
well as a strong record of postdoctoral research accomplishments and 
publications. The ideal candidate will have experience with ES and 
iPS cell culture (or alternatively mouse ES cell culture), culture of 
primary human cells, and the use of lentiviral vectors.  At minimum, 
candidates must have demonstrated experience with mammalian tissue 
culture technology, cell transfection, and basic molecular biology. 
Excellent organizational, communication and interpersonal skills are 
required.  Experience working in a collaborative research environment 
is strongly preferred.  A faculty level (non-tenure track) 
appointment may be considered based on the candidate's credentials.  
Interested individuals should send request for more information or a 
formal application with names of  3 references to Brigid Hogan PhD 
only at the e-mail address: stemcell at cellbio.duke.edu
Closing date for applications Feb 28th 2010

-- 
*****************************************
Debra L. Martin, Programs Manager
MIT
Vice President for Research Office, Rm 11-268
77 Massachusetts Avenue
Cambridge, MA  02139
617-258-0310, 617-252-1003 (fax)
debra at mit.edu
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