[Editors] MIT Research Digest, September 2006

Elizabeth Thomson thomson at MIT.EDU
Tue Sep 5 17:06:00 EDT 2006


MIT News Office
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MIT Research Digest, September 2006
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For Immediate Release
TUESDAY, SEP. 5, 2006
Contact: Elizabeth A. Thomson
Phone: 617-258-5402
Email: thomson at mit.edu

A monthly tip-sheet for journalists of recent research advances at 
the Massachusetts Institute of Technology. For the latest MIT 
research news, go to http://web.mit.edu/newsoffice/research.html

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
IN THIS ISSUE: Robotic Kayaks * Managing Nuclear Waste
How We Learn * New Cancer Treatment * Drug Safety
Earth History * Real Time Rome * e-Lens * Media Clash
Crab Nabbed * Exploring Alzheimer's * Definition: Planet
Perceptual Learning * Storing Carbon Dioxide
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

ROBOTIC KAYAKS
MIT researchers are working toward the day when a team of robots 
could be put into action like a team of Navy SEALs - doing such 
dangerous work as searching for survivors after hurricanes or 
sweeping harbors for mines. These engineers are taking small steps 
toward the holy grail of robotics - cooperative autonomy - making 
machines work together seamlessly to complete tasks with a minimum of 
human direction. The tool they're using is the simple kayak. The 
researchers are taking off-the-shelf, $500 plastic kayaks and fitting 
them with onboard computers, radio control, propulsion, steering, 
communications and more to create Surface Crafts for Oceanographic 
and Undersea Testing (SCOUTs). Much of the technology being tested is 
ultimately intended for use in underwater robots, or autonomous 
underwater vehicles (AUVs), but testing software on AUVs can easily 
become a multimullion-dollar experiment. "I want to have master's 
students and Ph.D. students that can come in, test algorithms and 
develop them on a shoestring budget," said Associate Professor John 
J. Leonard of mechanical engineering. This research was funded by the 
ONR and the MIT Sea Grant College Program. Acoustic communications 
hardware for the project was provided by the Woods Hole Oceanographic 
Institution.
PHOTOS AVAILABLE
MORE: http://web.mit.edu/newsoffice/2006/scout.html

MANAGING NUCLEAR WASTE
The Bush administration is eagerly pushing nuclear power as a way to 
help solve the U.S. energy crisis.  But in its new plan for nuclear 
waste management, the administration is taking the wrong approach, 
says an MIT professor who studies the nuclear energy industry. "My 
hope is that over time, the administration will rethink its 
priorities in this area," said Richard Lester, professor of nuclear 
engineering and director of the Industrial Performance Center. In an 
article published in Issues in Science and Technology, Lester argued 
that the Bush administration's plan, known as GNEP (Global Nuclear 
Energy Partnership), is not the best way to encourage further 
development of nuclear energy. GNEP, which President Bush announced 
earlier this year, is meant to stimulate the nuclear industry by 
coming up with better ways to manage spent nuclear fuel.  The plan 
focuses on reprocessing spent fuel, but Lester believes the 
administration should focus on finding regional storage facilities 
for the nuclear waste.
MORE: http://web.mit.edu/newsoffice/2006/nuclear-storage.html

HOW WE LEARN
Finally confirming a fact that remained unproven for more than 30 
years, researchers at MIT's Picower Institute for Learning and Memory 
report in the Aug. 25 issue of Science that certain key connections 
among neurons get stronger when we learn. "We show what everyone has 
always believed: LTP (long-term potentiation) is indeed induced in 
the hippocampus when learning occurs," said Mark Bear, Picower 
Professor of Neuroscience. "This is a big deal for neuroscientists 
because such evidence has been absent for the 30-plus years we have 
known about LTP." The findings described in the Bear paper and in a 
second, separate paper in the same issue of Science "substantially 
advance the case for LTP as a neural mechanism for memory," according 
to a commentary accompanying the papers. This work is supported by 
the Howard Hughes Medical Institute and the NIH.
PHOTO AVAILABLE
MORE: http://web.mit.edu/newsoffice/2006/ltp.html

NEW CANCER TREATMENT
Scientists at MIT, collaborating with an industrial team, are 
creating a proton-shooting system that could revolutionize radiation 
therapy for cancer. The goal is to get the system installed at major 
hospitals to supplement, or even replace, the conventional radiation 
therapy now based on x-rays. The fundamental idea is to harness the 
cell-killing power of protons -- the naked nuclei of hydrogen atoms 
-- to knock off cancer cells before the cells kill the patient. 
Worldwide, the use of radiation treatment now depends mostly on beams 
of x-rays, which do kill cancer cells but can also harm many normal 
cells that are in the way. What the researchers envision -- and what 
they're now creating -- is a room-size atomic accelerator costing far 
less than the existing proton-beam accelerators that shoot subatomic 
particles into tumors, while minimizing damage to surrounding normal 
tissues. They expect to have their first hospital system up and 
running in late 2007. Physicist Timothy Antaya, a technical 
supervisor in MIT's Plasma Science and Fusion Center (PSFC), leads 
the work. MIT is licensing the technology to Still River Systems. The 
PSFC's magnet work, which is key to the new system, has been funded 
by the DOE.
MORE: http://web.mit.edu/newsoffice/2006/proton.html

DRUG SAFETY
The MIT Center for Biomedical Innovation will work with the U.S. Food 
and Drug Administration to develop ways to monitor the safety of 
drugs that are already on the market. Currently, the FDA relies on 
voluntary reporting to track the adverse effects of drugs. The Center 
for Biomedical Innovation (CBI) will work to identify alternative 
ways to monitor the safety and efficacy of new and well-established 
pharmaceutical products and medical devices. In addition to voluntary 
reports the FDA receives from patients and the health-care community, 
CBI will use large sets of health-care data to recognize patterns 
that indicate unexpected efficacy or problems with safety. "Over the 
past year FDA has introduced several new policy and regulatory 
initiatives to improve post-marketing surveillance and strengthen the 
agency's oversight and protection of patients," said Dr. Scott 
Gottlieb, deputy commissioner for medical and scientific affairs. 
"This new partnership seeks to greatly enhance the ability of the FDA 
and the pharmaceutical industry to quickly determine the safety, 
efficacy or optimal use of a product."
MORE: http://web.mit.edu/newsoffice/2006/biobash-fda.html

EARTH HISTORY
The mass extinction of dinosaurs occurred about 66 million years ago, 
at the end of the Cretaceous Period (K) and the beginning of the 
Tertiary Period, known as the K-T boundary. A massive asteroid 
slammed into what is now the Gulf of Mexico about that time." About" 
is the key word here. The correlation is close, but not close enough 
for Samuel Bowring, a professor of geology in MIT's Department of 
Earth, Atmospheric and Planetary Sciences. Bowring, who thinks there 
is a correlation between the two events, firmly believes that it may 
be possible to more precisely date the sequence of events before, 
during and after the extinction. In 2003 Bowring launched the 
Earthtime initiative to bring together scientists from all over the 
world to work together to calibrate and sequence Earth history 
through the integration of high-precision geochronology and 
quantitative chronostratigraphy. Now, Earthtime has more than 200 
members, hailing from a variety of disciplines. Its official goal is 
to bring dating accuracy to better than 0.1 percent. That means in 
dating a 250-million-year-old fossil, results would be plus or minus 
250,000 years.
MORE: http://web.mit.edu/newsoffice/2006/earthtime.html

REAL TIME ROME
Real Time Rome, a pioneering MIT project that promises to usher in a 
new era of urban mapmaking, will have its worldwide debut at the 
Venice Biennale, the prestigious biannual exhibition of contemporary 
art and design that runs from Sept. 10 to Nov. 20. The MIT project 
uses data gathered, in real time and at an unprecedented scale, from 
cell phones and other wireless technologies, to better understand the 
patterns of daily life in Rome, and to illustrate what ubiquitous 
connectivity in an urban environment looks like. "In today's world, 
wireless mobile communications devices are creating new dimensions of 
interconnectedness between people, places and urban infrastructures," 
said project director Carlo Ratti, director of the SENSEable City Lab 
at MIT. "The goal of Real Time Rome is to use this connectivity to 
map the city in real time, which may ultimately lead to a deeper 
understanding of how modern cities function." The principal sponsor 
of Real Time Rome is Telecom Italia. Technical partners are the Rome 
public transportation authority (ATAC), Google, Samarcanda Taxi and 
the city of Rome.
IMAGES AVAILABLE
MORE: http://web.mit.edu/newsoffice/2006/realtime-rome.html

e-LENS
A walk down the street may someday be as rich with information as the 
web, thanks to the emergence of location-aware technology. MIT is at 
the vanguard of this movement with a project called Electronic Lens 
(eLens), an initiative of the MIT Media Lab. Headed by Professor 
William Mitchell and Visiting Scientist Federico Casalegno, eLens is 
defined by its focus on benefits for local citizens. Several research 
and commercial projects are also exploring the potential of 
location-aware services. Most rely on a tagging system - for example, 
physical tags attached to buildings - that can then be scanned and 
read by mobile camera phones. eLens is exploring the next wave of 
communications technology - building interactions that depend on 
where you are and what you want to know or say. In the eLens team's 
vision, you could aim your mobile phone at your child's school and 
start a voice thread to discuss cuts in after-school programs. Or you 
could let passersby know that the local folk music club serves great 
vegetarian meals.
MORE: http://web.mit.edu/newsoffice/2006/elens.html

MEDIA CLASH
The exploding complexity of the media in today's society has set up a 
clash between traditional media -- print, broadcast television, the 
recording industry and the corporate giants that own and sponsor them 
-- and the constantly mutating world of new media -- the Internet, 
"game worlds" and ever more powerful mobile devices and software. As 
MIT's Henry Jenkins explains in his new book, "Convergence Culture: 
Where Old and New Media Collide" (New York University Press), 
consumers are no longer content to be spoon-fed music, TV, movies and 
literature. They want to play with it, interact with it, parody it 
and analyze it -- with or without the by-your-leave of the primary 
producers. The battle for turf between the Goliaths of Time Warner 
and Fox and the masses of little Davids writing, playing and 
programming in their bedrooms is unlikely to be resolved anytime 
soon, Jenkins says.
MORE: http://web.mit.edu/newsoffice/2006/jenkins-media.html

CRAB NABBED
MIT researchers have confirmed the first sighting of a Dungeness crab 
in the Atlantic Ocean. The male, whose species is common on North 
America's West Coast, was caught off Thatcher Island, Massachusetts, 
earlier this summer by Lou Williams, captain of the fishing vessel 
Orin C. The origin of the crab is not known. One possibility is that 
it may have been purchased from a live seafood market and released. 
The size of the crab (18 cm) and its gender suggest it most likely 
arrived as an adult exotic species. Also known as invasive species or 
bioinvaders, exotic species are of concern because they can establish 
themselves in a new ecosystem, where they can proliferate and push 
out native species. The crab was caught while Williams was 
gillnetting for groundfish at 45 fathoms. Suspecting the crab to be a 
Dungeness, he took it to Brandy Wilbur, aquaculture specialist for 
MIT Sea Grant, and Eric Sabo, educator at the Gloucester Maritime 
Heritage Center, for verification. After distributing photographs of 
the crab to several scientists, the researchers received confirmation 
of the species, Cancer magister, from several experts.
PHOTO AVAILABLE
MORE: http://web.mit.edu/newsoffice/2006/crab.html

EXPLORING ALZHEIMER'S
Some people live to be 100 without falling victim to Alzheimer's 
disease. Li-Huei Tsai, who joined MIT this spring as Picower 
Professor of Neuroscience, wants to know why. Amyloid beta or Abeta 
(a protein fragment that accumulates in the brains of Alzheimer's 
patients) is a telltale sign of the disease, which affects 4 million 
Americans, most over age 65. Normally, the body manages to break down 
and eliminate these fragments, but in the aging brain, they tend to 
form insoluble plaques. To add to the mystery, some people function 
relatively normally with plaques nestled among their neurons, while 
others are virtually incapacitated. "There are people with a 
significant plaque load who can keep up with their daily lives," said 
Tsai, who has appointments in the Department of Brain and Cognitive 
Sciences and the Picower Institute for Learning and Memory. 
"Obviously, other factors are determining whether they have 
full-blown Alzheimer's." Tsai, who as a child in Taipei witnessed her 
grandmother's descent into dementia, is determined to unravel the 
thorny questions associated with neurodegenerative and psychiatric 
disorders.
PHOTO AVAILABLE
MORE: http://web.mit.edu/newsoffice/2006/alzheimers-abeta.html

DEFINITION: PLANET
The "United Nations" of astronomers has announced a new definition of 
what a planet is, slightly revising the description preferred by an 
international panel including an MIT professor that was tasked with 
the challenge. Members of the International Astronomical Union (IAU) 
voted on August 24 to define a planet as an object that is in orbit 
around the sun, is large enough for its own gravity to pull it into a 
nearly spherical shape, and has cleared the neighborhood around its 
orbit -- in other words, it has no other large bodies crossing its 
path. The third condition was added to the draft definition of a 
planet submitted to the IAU about a week earlier by MIT's Richard 
Binzel and colleagues. Binzel, a professor of planetary science in 
the Department of Earth, Atmospheric and Planetary Sciences, 
presented the final version of the resolution at the time of the 
final vote. The new definition means that Pluto will still be 
considered a planet. Technically, however, it will be a dwarf planet 
because it is smaller than Mercury.
MORE: http://web.mit.edu/newsoffice/2006/pluto-new.html

PERCEPTUAL LEARNING
The artist's trained eye can detect distinctions others can't; 
musicians pick up subtle changes in tone lost on the nonmusical. 
Brain researchers call these abilities perceptual learning. Following 
up on an accidental finding, MIT researchers at the Picower Institute 
for Learning and Memory and colleagues have uncovered a mechanism for 
this phenomenon. "Understanding this type of perceptual learning is 
important because it can reveal mechanisms of implicit memory 
formation and might be exploited to promote rehabilitation after 
brain damage. Detailed knowledge of how practice changes brain 
chemistry is likely to suggest new pharmacological and behavioral 
therapies to facilitate these changes," said Professor Mark Bear. The 
study, which appeared in an August issue of Neuron, was supported by 
the Howard Hughes Medical Institute and the National Eye Institute.
MORE: http://web.mit.edu/newsoffice/2006/perception.html

STORING CARBON DIOXIDE
Deep-sea sediments could provide a virtually unlimited and permanent 
reservoir for carbon dioxide, the gas that has been a primary driver 
of global climate change in recent decades, according to a team of 
scientists that includes a professor from MIT. The researchers 
estimate that seafloor sediments within U.S. territory are vast 
enough to store the nation's carbon dioxide (CO2) emissions for 
thousands of years to come. "The exciting thing about this paper is 
that we show that CO2 injected beneath the seafloor is sequestered 
permanently," said Charles Harvey, an associate professor in MIT's 
Department of Civil and Environmental Engineering. Harvey is a 
co-author of a paper on the work that appears in the Proceedings of 
the National Academy of Sciences. The leader of the work, Daniel 
Schrag, is at Harvard University. The research was funded by the DOE, 
the Merck Fund of the New York Community Trust and the Link 
Foundation.
MORE: http://web.mit.edu/newsoffice/2006/co2.html

--END--



-- 
=================================
Elizabeth A. Thomson
Assistant Director, Science & Engineering News
Massachusetts Institute of Technology
News Office, Room 11-400
77 Massachusetts Ave.
Cambridge, MA  02139-4307
617-258-5402 (ph); 617-258-8762 (fax)
<thomson at mit.edu>

<http://web.mit.edu/newsoffice/www>
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