From csbi-events at mit.edu  Wed Jan 30 09:50:57 2008
From: csbi-events at mit.edu (CSBi events)
Date: Wed, 30 Jan 2008 09:50:57 -0500
Subject: [CSBi-events] CSBi Seminar - Uri Alon - Feb. 8
Message-ID: <F7347652-59D7-495F-A616-3CB0BC70DF77@mit.edu>

Spring 2008 Seminar Series on Computational and Systems Biology
Friday, February 8, 2008
3:00 pm ? 4:00 pm
Room 3-270

Presenting:
Dr. Uri Alon
Department of Molecular Cell Biology and Department of Physics of  
Complex Systems, Weizmann Institute of Science, Rehovot, Israel

Title: Design Principles of Complex Systems
Abstract: Transcriptional networks are made of a collection of  
recurring interaction patterns known as network motifs.  The same  
handful of basic circuit elements seems to appear across organisms.   
Network motifs are thought to be selected because they carry out  
specific dynamical functions.  We will describe high-resolution  
experiments on living cells that demonstrate several such functions  
of network motifs, including sign-sensitive delays, speedup of  
network response, pulse generation and temporal programs of gene  
expression.  We will also describe network motifs in other biological  
networks, including signaling and neuronal networks.

[See U. Alon, Network motifs: theory and experimental approaches,  
Nat. Rev. Genetics 8, 450-461 (2007).]

Light refreshments to be served at 2:45 pm

Hosts:
Dr. Alexander van Oudenaarden, Department of Physics
Mei Lyn Ong, Graduate Student, Computational and Systems Biology


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