[CSBi-events] SAVE THE DATE: April 25th - CSBi seminar

[CSBi events]

Spring 2008 Seminar Series on Computational and Systems Biology

 

Friday, April 25, 2008

3:00 pm - 4:00 pm

Room 3-270

 

 

Presenting:

Professor Ned Wingreen

Department of Molecular Biology
Princeton University

 

Title: "Interactome Modeling adaptation in E. coli chemotaxis: precise,
robust, and optimized"

 

Abstract: The chemotaxis system of bacteria is remarkable for its
sensitivity to multiple ligands, over a wide range of concentrations. These
properties rely on cooperativity within clusters of receptors and on an
adaptation system in which chemoreceptors are modified by
methylation/demethylation. I'll discuss recent experiments that reveal new
aspects of adaptation, including "assistance neighborhoods" in which
tethered modifying enzymes can act on multiple receptors, and adaptive
variation in the sizes of receptor clusters.

 

Light refreshments to be served at 2:45 pm

 

Host: Alexander van Oudenaarden, Department of Physics

 

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