[CSBi-events] Friday, October 12, 2007; 3:00- 4:00 PM, Rm. 4-370 Reminder ! Fall 2007 Seminar Series on Computational and Systems Biology!

[CSBi events]

>
>
>Reminder !  Fall 2007 Seminar Series on Computational and Systems Biology!
>
>Friday, October 12, 2007; 3:00- 4:00 PM, Rm. 4-370
>Dr. Gurol Suel
>UT Southwestern Medical Center
>
>Title:
>Noisy out of necessity: Probabilistic behavior during cellular 
>differentiation.
>
>Light refreshments to be served at 2:45 p.m.
>
>Host:  Dr. Alexander van Oudenaarden
>Department of Physics
>
>Abstract
>
>Diverse organisms ranging from bacteria to mammalian stem cells 
>undergo pluripotent
>differentiation where a single cell can commit to one out of several 
>cell fates.
>How do underlying genetic circuits allow cells to "choose" a 
>specific cell fate and
>execute the appropriate differentiation program? To address this 
>question we investigate
>a simple bacterial differentiation system utilizing mathematical 
>modeling and quantitative
>single cell measurements. In particular we are interested in 
>elucidating the significance
>of circuit dynamics and stochastic behavior during cellular differentiation.
>
>Suel et al. Science 315, 1716-1719 (2007)
>Suel et al. Nature 440, 545-550 (2006)
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