[CSBi-events] Dr. Adam P. Arkin - Friday, 2/10/06

[CSBi events]

Dear CSBi Community,

You may want to take note of our CSBi Speaker Series seminar with 
guest speaker, Dr. Alan Arkin on Friday, February 10, 2006.  Thank 
you.

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Dr. Adam P. Arkin
Howard Hughes Medical Institute and
Departments of Bioengineering and Chemistry
University of California, Berkeley


"Adversity, Diversity and the Design for Dynamics and Evolution of 
Cellular Networks:
  From Bacterial Signaling to HIV gene expression"

Friday, February 10, 2006
Maclaurin Building (3-270)
3:00 - 4:00 p.m.
Light refreshments served beginning at 2:45 p.m.

Abstract

In times of adversity or stress organisms are forced to adapt or 
evolve to survive. In either case, the population may diversify its 
response; nongenetically in the former case and by mutation in the 
latter. Diversification may be shown to be an optimal survival 
strategy in certain types of environments and with particular sensing 
capabilities. Here we explore the molecular mechanisms and cellular 
network designs that adapt an organism to its particular niche and 
which control population diversity across the different time scales 
of adaptation and evolution. Using comparative genomics, quantitative 
measurement, and dynamical modeling, we examine the evolution and 
dynamics of particular cellular strategies from B. subtilis stress 
response diversification to exploitation of noise in the HIV gene 
expression program.

Host: Dr. Andrew Endy
Biological Engineering Division

Contact:	Isadora Deese
617.253.5494

Sponsored by CSBi
http://csbi.mit.edu/
Annual CSBi Seminar Series in Computational and Systems Biology
The entire MIT Community is welcome to attend!

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