[CSBi-events] LIDS Colloquium - Tues. February 8

[csbi-events@mit.edu]

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L I D S   C O L L O Q U I U M

LABORATORY FOR INFORMATION AND DECISION SYSTEMS

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CHALLENGES IN THE COMPUTATIONAL STRUCTURAL BIOLOGY OF VIRUSES

Peter C. Doerschuk
Electrical and Computer Engineering
Purdue University

Tuesday, February 8, 2005
4:00-5:00 pm
32-124

A short reception will follow on the 6th floor of the Dreyfoos Tower

Abstract:
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Structural biology is an important area of biology, both
pure and applied.  The computational aspects of structural
biology pose challenges in areas that are longstanding
research interests of EECS, e.g., statistical estimation,
pattern classification, and nonlinear programming.  The
success of high-throughput genetic sequencing and the
similar, though not as far advanced, success of
high-throughput protein structure determination by x-ray
crystallography and nuclear magnetic resonance imply that an
important frontier of structural biology concerns challenges
related to the interactions of multiple macromolecular
molecules in what are essentially nano-machines.  In this
talk, some of these challenges will be described and results
concerning the structural biology of viruses will be used as
illustrations of the types of systems, control, and signal
processing problems that arise.

Biography:
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Peter Doerschuk is a Professor of Electrical and Computer
Engineering and Biomedical Engineering at Purdue University.
He received BSEE, MSEE, and PhD degrees from MIT in EECS in
1977, 1979, and 1985, respectively and an MD degree from
Harvard Medical School (HST) in 1987.  After a postdoc at
LIDS he joined Purdue in 1990.  His research interests are
in computational biology and a variety of areas in
estimation, dynamical systems, and computation motivated by
computational biology requirements.

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Dawn Davis Loring
Communications Coordinator
Computational and Systems Biology (CSBi)
Phone: (617) 324-0150
Fax: (617) 324-0081

Massachusetts Institute of Technology
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Building 68 - Room 459
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