From csbi-events at mit.edu Wed Nov 3 15:26:40 2004 From: csbi-events at mit.edu (csbi-events@mit.edu) Date: Wed, 03 Nov 2004 15:26:40 -0500 Subject: [CSBi-events] Meet the CSBi Research Groups and CSB Graduate Students Message-ID: <5.2.1.1.2.20041103152538.00c1e518@po14.mit.edu> Meet the CSBi Research Groups AND Welcome MIT's First Class of Computational & Systems Biology Graduate Students Monday, November 15th Walker Memorial Lounge (building 50) 3:00-7:00 PM Enjoy short faculty talks, posters and refreshments. Contact: Darlene Ray for more information dray at mit.edu 617-253-3874 PLEASE DO NOT RESPOND TO THIS E-MAIL. SEE CONTACT INFO ABOVE. Dawn Davis Loring Communications Coordinator Computational and Systems Biology (CSBi) Phone: (617) 324-0150 Fax: (617) 324-0081 Massachusetts Institute of Technology 77 Massachusetts Avenue Building 68 - Room 459 Cambridge, MA 02139 From csbi-events at mit.edu Fri Nov 5 10:27:14 2004 From: csbi-events at mit.edu (csbi-events@mit.edu) Date: Fri, 05 Nov 2004 10:27:14 -0500 Subject: [CSBi-events] Seminar: From Mouse Genetics to Human Therapeutics Message-ID: <5.2.1.1.2.20041105102413.031f6c40@po14.mit.edu> From Mouse Genetics to Human Therapeutics Time: Wednesday (11/10/04) at 4:00 PM Location: 68-181 Gary Peltz, M.D., Ph.D Department of Genetics and Genomics ROCHE, Palo Alto, CA Our understanding of genetic factors effecting human disease susceptibility and the response to drug treatment is advanced by analysis of murine genetic models. As one example, a murine genetic model of osteoporosis was analyzed, and a novel pathway regulating bone development was identified. However, a significant amount of time and cost is associated with the conventional methods used for mouse genetic analysis. A novel computational method was developed to reduce the time and cost required for mouse genetic analysis. This method identifies a causative genetic factor by correlating a pattern of observable physiological or pathological differences among selected strains of mice with the pattern of genetic variation. A haplotypic map of the genome, based upon 150,000 SNPs identified from analysis of 1,900 genes across 20 commonly used laboratory mouse strains (http://mouseSNP.roche.com), was produced. This map was used to develop a method for rapid, haplotype-based, computational identification of the genetic basis for observed physiologic and pathologic differences among inbred strains. This computational method correctly predicted the genetic basis for strain-specific differences in multiple biologically important phenotypic traits, and was used to identify a novel allele-specific enhancer element regulating H2-Ea expression. This method is now being used to analyze the mechanism of action and metabolism of a commonly prescribed medication. References In silico genetics: identification of a functional element regulating H2-Ealpha gene expression. Science 306:690, 2004 Regulation of bone mass in mice by the lipoxygenase gene Alox15. Science 303:229, 2004 Contact: Peter Sandy, Ph.D. Center for Cancer Research Tel: 617-324-8700 Email: psandy at mit.edu PLEASE DO NOT RESPOND TO THIS EMAIL, SEE CONTACT INFO ABOVE. Dawn Davis Loring Communications Coordinator Computational and Systems Biology (CSBi) Phone: (617) 324-0150 Fax: (617) 324-0081 Massachusetts Institute of Technology 77 Massachusetts Avenue Building 68 - Room 459 Cambridge, MA 02139 From csbi-events at mit.edu Fri Nov 12 11:49:11 2004 From: csbi-events at mit.edu (csbi-events@mit.edu) Date: Fri, 12 Nov 2004 11:49:11 -0500 Subject: [CSBi-events] HPC User Meeting - Wednesday, November 17 Message-ID: <5.2.1.1.2.20041112114210.00c0a070@po14.mit.edu> HPC User Meeting Approaches and Trends in Neural Computation Jay Best, Neurocomputing Group Wednesday, November 17 NE47-189 5pm Food will be served Contact: James Evans (jgevans at mit.edu) 617-324-0300 PLEASE DO NOT RESPOND TO THIS EMAIL, SEE CONTACT INFO ABOVE. Dawn Davis Loring Communications Coordinator Computational and Systems Biology (CSBi) Phone: (617) 324-0150 Fax: (617) 324-0081 Massachusetts Institute of Technology 77 Massachusetts Avenue Building 68 - Room 459 Cambridge, MA 02139 From csbi-events at mit.edu Fri Nov 12 11:49:59 2004 From: csbi-events at mit.edu (csbi-events@mit.edu) Date: Fri, 12 Nov 2004 11:49:59 -0500 Subject: Out of Office AutoReply: [CSBi-events] HPC User Meeting - Wednesd ay, November 17 Message-ID: <339D68B133EAD311971E009027DC4797CCB6A6@montecarlo.cgr.harvard.edu> Al Daneau is out of the office. I will be back on Friday November 12 From csbi-events at mit.edu Fri Nov 12 11:54:18 2004 From: csbi-events at mit.edu (csbi-events@mit.edu) Date: Fri, 12 Nov 2004 11:54:18 -0500 Subject: [CSBi-events] Monday, Nov. 15 - Meet the CSBi Research Groups Message-ID: <5.2.1.1.2.20041112115333.032abf38@po14.mit.edu> Meet the CSBi Research Groups Welcome MIT's First Class of Computational & Systems Biology Graduate Students Monday, November 15th Walker Memorial Lounge (building 50) 3:00-7:00 PM Enjoy short faculty talks, posters and refreshments. Contact: Darlene Ray for more information dray at mit.edu 617-253-3874 Dawn Davis Loring Communications Coordinator Computational and Systems Biology (CSBi) Phone: (617) 324-0150 Fax: (617) 324-0081 Massachusetts Institute of Technology 77 Massachusetts Avenue Building 68 - Room 459 Cambridge, MA 02139 From csbi-events at mit.edu Tue Nov 16 15:16:57 2004 From: csbi-events at mit.edu (csbi-events@mit.edu) Date: Tue, 16 Nov 2004 15:16:57 -0500 Subject: [CSBi-events] CSBi Symposium 2005 - Registration is Open! Message-ID: <1100636217.419a6039a089b@webmail.mit.edu> CSBi 2005 Symposium in Systems Biology "Cells, Circuits & Computation" January 13 & 14, 2005 MIT Wong Auditorium Building E-51, Cambridge, MA TOPICS: * Systems and Languages * Multivariate Modelling of Cell Signaling * Network Analysis in Human Disease * Molecular and Cellular Analysis on a Microscale * New Chemical Probes for Analyzing Complex Systems Selected Speakers Include: Academia * Mark Burns, University of Michigan * Andrew Ellington, University of Texas at Austin * Lakshminarayanan Mahadevan, Harvard University * Vamsi Mootha, Broad Institute * Jim Schaff, University of Connecticut Health Center * Steve Altschuler, Harvard University * Lani Wu, Harvard University Academia ? MIT * Alan Grodzinsky * Barbara Imperiali * Collin Stultz, MIT/Harvard * Subra Suresh * Bruce Tidor * Jacob White Industry * John Foster, Innovative Micro-Technology * David Searls, GlaxoSmithKline The Symposium also features: * Industry Perspectives * Poster Session and Awards * Selected Speakers Chosen from Poster Submissions * Reception and Networking Lunches Dates to Remember: * Registration is required by December 31, 2004 * Poster/Abstract Submission deadline is December 15, 2004 (2-3 Speakers will be selected to deliver oral presentations) Space is Limited - Register Early! http://csbi.mit.edu/events/annualsymposium/2005 For more information, contact: csbi AT mit DOT edu From csbi-events at mit.edu Wed Nov 17 23:11:16 2004 From: csbi-events at mit.edu (csbi-events@mit.edu) Date: Wed, 17 Nov 2004 23:11:16 -0500 Subject: [CSBi-events] CSBi Symposium 2005 - Registration is Open! Message-ID: Hi, I am out of office from thursday (18) afternoon to friday (19). In case of urgency, you can reach my cell at 617-259-7388. -Ashwani On Nov 16, 2004, at 3:16 PM, csbi-events at MIT.EDU wrote: > CSBi 2005 Symposium in Systems Biology > "Cells, Circuits & Computation" > > January 13 & 14, 2005 > MIT Wong Auditorium > Building E-51, Cambridge, MA > > > TOPICS: > > * Systems and Languages > * Multivariate Modelling of Cell Signaling > * Network Analysis in Human Disease > * Molecular and Cellular Analysis on a Microscale > * New Chemical Probes for Analyzing Complex Systems > > Selected Speakers Include: > > Academia > * Mark Burns, University of Michigan > * Andrew Ellington, University of Texas at Austin > * Lakshminarayanan Mahadevan, Harvard University > * Vamsi Mootha, Broad Institute > * Jim Schaff, University of Connecticut Health Center > * Steve Altschuler, Harvard University > * Lani Wu, Harvard University > > Academia ? MIT > * Alan Grodzinsky > * Barbara Imperiali > * Collin Stultz, MIT/Harvard > * Subra Suresh > * Bruce Tidor > * Jacob White > > Industry > * John Foster, Innovative Micro-Technology > * David Searls, GlaxoSmithKline > > The Symposium also features: > > * Industry Perspectives > * Poster Session and Awards > * Selected Speakers Chosen from Poster Submissions > * Reception and Networking Lunches > > Dates to Remember: > > * Registration is required by December 31, 2004 > * Poster/Abstract Submission deadline is December 15, 2004 > (2-3 Speakers will be selected to deliver oral presentations) > > > Space is Limited - Register Early! > http://csbi.mit.edu/events/annualsymposium/2005 > > For more information, contact: csbi AT mit DOT edu > > _______________________________________________ > CSBi-events mailing list > CSBi-events at mit.edu > http://mailman.mit.edu/mailman/listinfo/csbi-events From csbi-events at mit.edu Wed Nov 17 23:11:45 2004 From: csbi-events at mit.edu (csbi-events@mit.edu) Date: Wed, 17 Nov 2004 23:11:45 -0500 Subject: Out of Office AutoReply: [CSBi-events] HPC User Meeting - Wednesd ay, November 17 Message-ID: Hi, I am out of office from thursday (18) afternoon to friday (19). In case of urgency, you can reach my cell at 617-259-7388. -Ashwani On Nov 12, 2004, at 11:49 AM, csbi-events at MIT.EDU wrote: > Al Daneau is out of the office. > > I will be back on Friday November 12 > > > _______________________________________________ > CSBi-events mailing list > CSBi-events at mit.edu > http://mailman.mit.edu/mailman/listinfo/csbi-events From csbi-events at mit.edu Wed Nov 17 23:13:38 2004 From: csbi-events at mit.edu (csbi-events@mit.edu) Date: Wed, 17 Nov 2004 23:13:38 -0500 Subject: [CSBi-events] Seminar: From Mouse Genetics to Human Therapeutics Message-ID: <39AF13BF-3918-11D9-B675-000A95E98678@mit.edu> Hi, I am out of office from thursday (18) afternoon to friday (19). In case of urgency, you can reach my cell at 617-259-7388. -Ashwani On Nov 5, 2004, at 10:27 AM, csbi-events at MIT.EDU wrote: > From Mouse Genetics to Human Therapeutics > > Time: Wednesday (11/10/04) at 4:00 PM > Location: 68-181 > > Gary Peltz, M.D., Ph.D > > Department of Genetics and Genomics > ROCHE, Palo Alto, CA > > > Our understanding of genetic factors effecting human disease > susceptibility and the response to drug treatment is advanced by > analysis of murine genetic models. As one example, a murine genetic > model of osteoporosis was analyzed, and a novel pathway regulating bone > development was identified. However, a significant amount of time and > cost is associated with the conventional methods used for mouse genetic > analysis. A novel computational method was developed to reduce the > time > and cost required for mouse genetic analysis. This method identifies a > causative genetic factor by correlating a pattern of observable > physiological or pathological differences among selected strains of > mice > with the pattern of genetic variation. A haplotypic map of the genome, > based upon 150,000 SNPs identified from analysis of 1,900 genes across > 20 commonly used laboratory mouse strains (http://mouseSNP.roche.com), > was produced. This map was used to develop a method for rapid, > haplotype-based, computational identification of the genetic basis for > observed physiologic and pathologic differences among inbred strains. > This computational method correctly predicted the genetic basis for > strain-specific differences in multiple biologically important > phenotypic traits, and was used to identify a novel allele-specific > enhancer element regulating H2-Ea expression. This method is now being > used to analyze the mechanism of action and metabolism of a commonly > prescribed medication. > > References > > In silico genetics: identification of a functional element > regulating H2-Ealpha gene expression. Science 306:690, 2004 > > Regulation of bone mass in mice by the lipoxygenase gene Alox15. > Science > 303:229, 2004 > > Contact: > Peter Sandy, Ph.D. > Center for Cancer Research > Tel: 617-324-8700 > Email: psandy at mit.edu > > PLEASE DO NOT RESPOND TO THIS EMAIL, SEE CONTACT INFO ABOVE. > > Dawn Davis Loring > Communications Coordinator > Computational and Systems Biology (CSBi) > Phone: (617) 324-0150 > Fax: (617) 324-0081 > > Massachusetts Institute of Technology > 77 Massachusetts Avenue > Building 68 - Room 459 > Cambridge, MA 02139 _______________________________________________ > CSBi-events mailing list > CSBi-events at mit.edu > http://mailman.mit.edu/mailman/listinfo/csbi-events From csbi-events at mit.edu Wed Nov 17 23:11:47 2004 From: csbi-events at mit.edu (csbi-events@mit.edu) Date: Wed, 17 Nov 2004 23:11:47 -0500 Subject: [CSBi-events] HPC User Meeting - Wednesday, November 17 Message-ID: Hi, I am out of office from thursday (18) afternoon to friday (19). In case of urgency, you can reach my cell at 617-259-7388. -Ashwani On Nov 12, 2004, at 11:49 AM, csbi-events at MIT.EDU wrote: > HPC User Meeting > > Approaches and Trends in Neural Computation > Jay Best, Neurocomputing Group > > Wednesday, November 17 > NE47-189 > 5pm > > Food will be served > > Contact: James Evans (jgevans at mit.edu) > 617-324-0300 > > PLEASE DO NOT RESPOND TO THIS EMAIL, SEE CONTACT INFO ABOVE. > > Dawn Davis Loring > Communications Coordinator > Computational and Systems Biology (CSBi) > Phone: (617) 324-0150 > Fax: (617) 324-0081 > > Massachusetts Institute of Technology > 77 Massachusetts Avenue > Building 68 - Room 459 > Cambridge, MA 02139 _______________________________________________ > CSBi-events mailing list > CSBi-events at mit.edu > http://mailman.mit.edu/mailman/listinfo/csbi-events From csbi-events at mit.edu Wed Nov 17 23:14:25 2004 From: csbi-events at mit.edu (csbi-events@mit.edu) Date: Wed, 17 Nov 2004 23:14:25 -0500 Subject: [CSBi-events] Meet the CSBi Research Groups and CSB Graduate Students Message-ID: <5579EFFC-3918-11D9-B675-000A95E98678@mit.edu> Hi, I am out of office from thursday (18) afternoon to friday (19). In case of urgency, you can reach my cell at 617-259-7388. -Ashwani On Nov 3, 2004, at 3:26 PM, csbi-events at MIT.EDU wrote: > Meet the CSBi Research Groups > > AND > > Welcome MIT's First Class of Computational & Systems Biology Graduate > Students > > Monday, November 15th > Walker Memorial Lounge (building 50) > 3:00-7:00 PM > > Enjoy short faculty talks, posters and refreshments. > > Contact: Darlene Ray for more information > dray at mit.edu > 617-253-3874 > > PLEASE DO NOT RESPOND TO THIS E-MAIL. SEE CONTACT INFO ABOVE. > > > Dawn Davis Loring > Communications Coordinator > Computational and Systems Biology (CSBi) > Phone: (617) 324-0150 > Fax: (617) 324-0081 > > Massachusetts Institute of Technology > 77 Massachusetts Avenue > Building 68 - Room 459 > Cambridge, MA 02139 _______________________________________________ > CSBi-events mailing list > CSBi-events at mit.edu > http://mailman.mit.edu/mailman/listinfo/csbi-events From csbi-events at mit.edu Wed Nov 17 23:11:44 2004 From: csbi-events at mit.edu (csbi-events@mit.edu) Date: Wed, 17 Nov 2004 23:11:44 -0500 Subject: [CSBi-events] Monday, Nov. 15 - Meet the CSBi Research Groups Message-ID: Hi, I am out of office from thursday (18) afternoon to friday (19). In case of urgency, you can reach my cell at 617-259-7388. -Ashwani On Nov 12, 2004, at 11:54 AM, csbi-events at MIT.EDU wrote: > Meet the CSBi Research Groups > Welcome MIT's First Class of Computational & Systems Biology Graduate > Students > > Monday, November 15th > Walker Memorial Lounge (building 50) > 3:00-7:00 PM > > Enjoy short faculty talks, posters and refreshments. > > Contact: Darlene Ray for more information > dray at mit.edu > 617-253-3874 > > Dawn Davis Loring > Communications Coordinator > Computational and Systems Biology (CSBi) > Phone: (617) 324-0150 > Fax: (617) 324-0081 > > Massachusetts Institute of Technology > 77 Massachusetts Avenue > Building 68 - Room 459 > Cambridge, MA 02139 _______________________________________________ > CSBi-events mailing list > CSBi-events at mit.edu > http://mailman.mit.edu/mailman/listinfo/csbi-events From csbi-events at mit.edu Wed Nov 24 11:19:30 2004 From: csbi-events at mit.edu (csbi-events@mit.edu) Date: Wed, 24 Nov 2004 11:19:30 -0500 Subject: [CSBi-events] Teranode Seminar and Workshops Message-ID: CSBi is Sponsoring a Seminar and Workshops on the TERANODE Design Suite, an informatics solution for integrating computational and experimental biology. There will be an introductory seminar followed by two workshops to provide interactive demonstrations and hands-on technical assistance for researchers interested in using the software. Introduction to Teranode Thursday, December 2, 2004 Bldg. 68, Room 121 10:00 AM Workshops Space is limited for the workshops!! Please contact Linda Earle 617-324-0074 (lkn at mit.edu) to reserve your place. Thursday, December 2, 2004 Protocol Modeler Demonstration Bldg1-Room115 1:00 - 2:00 PM Biological Modeler Demonstration Bldg1-Room115 2:00 - 4:00 PM Friday, December 3, 2004 Biological Modeler Hands-on Workshop Bldg1-Room115 10:00 AM - 1:00 PM Please contact Nika Stoop-Myer (csmyer at mit.edu) or Linda Earle (lkn at mit.edu) for more information. From csbi-events at mit.edu Wed Nov 24 20:40:37 2004 From: csbi-events at mit.edu (csbi-events@mit.edu) Date: Wed, 24 Nov 2004 20:40:37 -0500 Subject: [CSBi-events] Jim Hogan/BOS/US/Vpharm is out of the office. Message-ID: I will be out of the office starting 11/24/2004 and will not return until 12/01/2004. I will respond to your message when I return. From csbi-events at mit.edu Mon Nov 29 12:09:50 2004 From: csbi-events at mit.edu (csbi-events@mit.edu) Date: Mon, 29 Nov 2004 12:09:50 -0500 Subject: [CSBi-events] Fwd: Welcome to the "CSBi-events" mailing list Message-ID: From csbi-events at mit.edu Tue Nov 30 14:59:04 2004 From: csbi-events at mit.edu (csbi-events@mit.edu) Date: Tue, 30 Nov 2004 14:59:04 -0500 Subject: [CSBi-events] CSBi Seminar this Friday, December 3 Message-ID: <1101844744.41acd10817d93@webmail.mit.edu> CSBi Seminar- "How does a protein find its site on DNA?" Dr. Leonid Mirny Harvard-MIT Division of Health Sciences & Technology Friday, December 3, 2004 McGovern Auditorium Whitehead Institute 3:00 PM Host: Chris Burge Contact: Brenda Pepe x3-6077 http://csbi.mit.edu PLEASE DO NOT RESPOND TO THIS E-MAIL, SEE CONTACT INFO ABOVE.