From dloring at MIT.EDU Tue Feb 17 10:32:25 2004 From: dloring at MIT.EDU (Dawn Davis Loring) Date: Tue, 17 Feb 2004 10:32:25 -0500 Subject: [CSBi-events] Spinning Disc Confocal Introduction Training Message-ID: <5.1.0.14.2.20040217102850.03988c88@po14.mit.edu> CSBi Special Event Spinning Disc Confocal Introduction Training Tuesday February 24 By Reservation from 1:00 4:00 PM Whitehead Institute Please reserve by February 19th Contact: Nicki Watson (watson at wi.mit.edu) ULTRAVIEW LIVE CELL IMAGER from PerkinElmer* The Ultraview is an automated high resolution live cell confocal imaging system. www.perkinelmer.com/lifesciences *PerkinElmer representatives will be on hand to assist Potential applications: * Monitor complete cell division cycles and cellular activity without damaging your sample. * Capture real-time 3-D images of living cells without phototoxicity or photobleaching damage to the cell, GFP or fluorscent reporter. * Ideal for fluorescent protein studies, signaling pathway analysis, membrane trafficking experiments and more. Dawn Davis Loring Communications Coordinator Computational and Systems Biology (CSBi) Phone: (617) 324-0150 Fax: (617) 324-0081 Massachusetts Institute of Technology 77 Massachusetts Avenue Building 68 - Room 459 Cambridge, MA 02139 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://mailman.mit.edu/pipermail/csbi-events/attachments/20040217/d5bdf27d/attachment.htm From dloring at MIT.EDU Thu Feb 19 09:24:00 2004 From: dloring at MIT.EDU (Dawn Davis Loring) Date: Thu, 19 Feb 2004 09:24:00 -0500 Subject: [CSBi-events] APPLIED MATHEMATICS COLLOQUIUM (Joint with Bioinformatics Seminar) Message-ID: <5.1.0.14.2.20040218161002.0396d5f8@po14.mit.edu> From Amy Keating: APPLIED MATHEMATICS COLLOQUIUM (Joint with Bioinformatics Seminar) FOLDING ALGORITHMS FOR PROTEIN STRUCTURE PREDICTION DATE: MONDAY, FEBRUARY 23, 2004 TIME: 4:15 PM LOCATION: Building 2, Room 105 Reception at 3:30 PM in Building 2, Room 349. Guest: PHILIP BRADLEY, University of Washington ABSTRACT: To reach their biologically active state, newly synthesized proteins spontaneously fold from an extended, linear conformation into a compact three-dimensional structure. This remarkable self-assembly process, protein folding, is guided by the amino acid sequence of the protein to a unique final state. Despite several decades of intensive study the process by which sequence determines structure is still not well understood; in particular it is not currently possible to predict a protein's native three-dimensional structure given only its sequence. Recently, however, a class of prediction algorithms based on protein fragment assembly have made considerable headway towards the goal of generating low-resolution structure predictions. In this talk I will introduce the protein folding problem, describe these new algorithms, highlight their strengths and weaknesses, and discuss current research directed at improving the reliability and accuracy of their predictions. Dawn Davis Loring Communications Coordinator Computational and Systems Biology (CSBi) Phone: (617) 324-0150 Fax: (617) 324-0081 Massachusetts Institute of Technology 77 Massachusetts Avenue Building 68 - Room 459 Cambridge, MA 02139 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://mailman.mit.edu/pipermail/csbi-events/attachments/20040219/42cd858f/attachment.htm From dloring at MIT.EDU Tue Feb 24 09:45:25 2004 From: dloring at MIT.EDU (Dawn Davis Loring) Date: Tue, 24 Feb 2004 09:45:25 -0500 Subject: [CSBi-events] CSBi HPC UserGroup Meeting Message-ID: <5.1.0.14.2.20040224094019.02f587b8@po14.mit.edu> NOTICE: WEDNESDAY, FEBRUARY 25th Meeting: CSBi High Performance Computing UserGroup Title: "MPI: An Overview of Message Passing Part Two" Speaker: Dr. Kirk E. Jordan, Emerging Solutions Executive, IBM Life Sciences Location: 500 Technology Square (NE47) room 189 When: 5pm Wednesday February 25th Dinner will be served. For more information, please contact James Evans at 4-0300, jgevans at mit.edu Dawn Davis Loring Communications Coordinator Computational and Systems Biology (CSBi) Phone: (617) 324-0150 Fax: (617) 324-0081 Massachusetts Institute of Technology 77 Massachusetts Avenue Building 68 - Room 459 Cambridge, MA 02139 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://mailman.mit.edu/pipermail/csbi-events/attachments/20040224/3ee87d64/attachment.htm From mlinden at MIT.EDU Thu Feb 26 09:51:55 2004 From: mlinden at MIT.EDU (Monica L Linden) Date: Thu, 26 Feb 2004 09:51:55 -0500 Subject: [CSBi-events] Brain Lunch - Monday Message-ID: <5.1.0.14.2.20040226094832.01d2a698@po11.mit.edu> Monday March 1, 2004 Noon E25-401 Gabriel Kreiman Reading out information from the macaque inferior temporal cortex Poggio Lab Primates have an extraordinary capacity to visually recognize objects. This ability depends on the function of the inferior temporal (IT) cortex in the macaque brain. Neurons in inferior temporal cortex are selective for complex stimuli including faces and objects. How well can we decode the activity in IT to be able to interpret which visual stimuli were presented to the monkey? In collaboration with Chou Hung in Jim DiCarlo?s lab, we are recording neuronal activity while a monkey is presented with a set of 78 different visual stimuli. We are focusing on three different sources of neuronal activity multi-unit activity (MUA) from single electrodes, single-unit activity (SUA) and local field potentials (LFP). The neuronal activity is fed to a classifier (Fisher linear discriminant of Support Vector Machine) to learn the mapping from neuronal responses to visual stimuli. We will describe the algorithms used to predict the stimuli based on the neuronal activity and their dependency on different possible inputs to the classifiers. We will report how the performance of the classifier depends on the type of input (MUA, LFP), on the time interval, on the timing of spikes and on the number of recording sites (assuming independence). This work is a collaboration between Alec Shkolnik, Chou Hung, Gabriel Kreiman, Jim DiCarlo and Tommy Poggio. Pizza will be served! All faculty, postdocs and students are invited to attend. Interested in giving a Brain Lunch talk? Dates still available for this semester. Send me an email - ASAP For questions about Brain Lunch, contact Monica Linden ( mlinden at mit.edu ). See you on Monday, Monica Linden Brain Lunch Coordinator -------------- next part -------------- An HTML attachment was scrubbed... URL: http://mailman.mit.edu/pipermail/csbi-events/attachments/20040226/d86993ef/attachment.htm