[Crib-list] Speaker: Robin Friedman -- Computational Research in Boston Seminar -- Friday, August 6, 2010 -- 12:30 PM -- Room 32-141 (Stata)

[Shirley Entzminger]

		COMPUTATIONAL RESEARCH in BOSTON SEMINAR


DATE:		Friday, August 6, 2010
TIME:		12:30 PM
LOCATION:	Building 32, Room 141 (Stata Center)

(Refreshments will be provided outside Room 32-141 at 12:15 PM.)


TITLE:		High-throughput Sequencing and Computation in the search 
		for a Gene Expression Code


SPEAKER:	Robin Friedman  (M. I. T.)

ABSTRACT:

The study of biology has historically been limited by a small set of slow 
and low-throughput tools. However, technological advances have led to an 
explosion in the amount of data available to biologists in the past few 
years. Almost overnight, computation has become an inextricable component 
of cutting- edge biology, especially in the field of gene expression, the 
study of how genetic sequence is translated into phenotypic effects. This 
talk will provide an overview of the impact of high-throughput sequencing 
on the study of gene expression from a computer science perspective. In 
particular, two examples will be presented: comparative genomics for 
microRNA binding sites and experimental quantification of transcription 
factor binding specificity.

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Massachusetts Institute of Technology
Cambridge, MA  02139

http://math.mit.edu/crib/