[Crib-list] SPEAKER: MALA L. RADHAKRISHNAN -- Computational Research in Boston Seminar -- Friday, March 7, 2008 -- 12:30 PM == Room 32-144 (Stata)

[Shirley Entzminger]

 			COMPUTATIONAL RESEARCH in BOSTON SEMINAR


Date:		FRIDAY, MARCH 7, 2008
Time:		12:30 PM
Location:	Building 32, Room 144  (STATA CENTER)

(Pizza and beverages will be provided at 12:15 PM.)


Title:		COMPUTATIONAL DRUG DESIGN AND ANALYSIS:
 		A MULTIFACETED APPROACH


Speaker:	MALA L. RADHAKRISHNAN  (Wellesley College)


ABSTRACT:

Computation is playing an increasingly significant role in the design and 
analysis of drug molecules to treat disease.  Using the HIV-1 protease system 
and other systems as case studies, I will address the many ways in which 
computation can specifically tackle system-specific challenges such as drug 
resistance and drug degradation.  Theory, physics-based models, optimization 
methods, and phenomological larger-scale models can all be integrated into a 
multi-facted approach to better understand the action of current drugs and to 
design novel ones for the future.

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Massachusetts Institute of Technology
Cambridge, MA  02139


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Steven G. Johnson:  stevenj at math.mit.edu
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