[bioundgrd] Biology UROP Opportunity in Laub Lab

[Joyce Roberge]

Biology UROP Opportunity: Regulatory Principles of Cell Cycle Control in Bacteria
We are seeking a motivated undergraduate student to work in the lab of Dr. Michael Laub in the Biology Department. The Laub lab (http://laublab.mit.edu/) is generally interested in how bacteria process information; projects in the lab include high-throughput approaches to identify evolutionary principles guiding regulatory interactions as well as dissecting molecular mechanisms of cell sensing and cell cycle control. The undergraduate will work directly with Dr. Jayme Dyer, a postdoctoral fellow, on principles of cell cycle regulation in the bacterium Caulobacter crescentus. Specifically, we are working to understand the molecular mechanism underpinning a DNA replication checkpoint that prevents cell cycle progression when DNA replication is blocked. The project will include traditional molecular biology and bacterial genetics, and may include microscopy, flow cytometry, sequencing, and other current methods.
Initial position is for the Spring 2016 semester with the potential to extend into the summer and beyond. Position is for credit, with the potential for pay in the future.
Prerequisites: 7.01 and 7.02, preference for 7.03
Interested students should send a CV and a cover letter to Dr. Jayme Dyer (jayme at mit.edu<mailto:jayme at mit.edu>) explaining their interest in the project, relevant coursework and prior research experience (if any), and how a UROP in the Laub lab will contribute to their educational and career goals.

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