[bioundgrd] FW: Request for UROP advertisement

[MacKenzie Outlund]

> 10/17/2008
> Fall 2008 or IAP 2009
> UROP Department/Lab/Center: Biology/Koch Institute for Integrative
> Cancer Research
> Faculty Supervisor: Prof. Phillip A Sharp
> Supervisor: Dr. Anthony K L Leung
> 
> The role of microRNAs in mouse embryonic stem cells
> 
> Pluripotency or the ability to give rise to several cell types by
> embryonic stem cells lies in gene regulation. We are studying how such
> properties of these stem cells are maintained by microRNAs, a new
> class of regulatory short RNAs. Though small in size, microRNAs
> probably represent the largest set of regulators of gene expression.
> They constitute 1-4% of human genes and are predicted to regulate one-
> third of all genes. We used a new biochemical method to isolate
> potential microRNA-regulated gene targets. We are now currently
> recruiting a motivated undergraduate to join a team of 1 postdoctoral
> fellow, 2 PhD students and 1 undergraduate to dissect computationally
> the functions of these targets in keeping embryonic stem cells
> pluripotent and followed by on-bench experiments.
> 
> Prerequisites: Candidates must have a strong interest in biological
> research and should be familiar with Perl and SQL. The ideal candidate
> is a sophomore or junior who has completed 7.01 and (preferably 7.02)
> and is interested in continuing in the lab for the upcoming IAP and
> multiple semesters.
> 
> Contact: Please send a resume with course list/GPA score, brief
> statement of interest, and if applicable, brief summary of research
> experience to Anthony Leung (akleung at mit.edu); http://web.mit.edu/sharplab/
> .
> 
> 
> ---------------
> Anthony Leung
>   c/o Sharp Lab
>   Center for Cancer Research
>   77 Massachusetts Avenue E17-526
>   Cambridge, MA 02139
> 
>   Phone: (617) 253-0265
>   Fax: (617) 253-3867
>   akleung at mit.edu
>