[bioundgrd] (TODAY!) BIOLOGY COLLOQUIUM- Dr. Hannele Ruohola-Baker

[Rachel McPherson]

BIOLOGY COLLOQUIUM
Monday, March 20, 2006
Dr. Hannele Ruohola-Baker
University of Washington
"MicroRNAs Regulate Stem Cell Division"
32-123 Stata Center Auditorium
4pm (refreshments at 3:30)
Hosted by Irena Ivanovska

Dr. Ruohola-Baker's laboratory has been focused 
on understanding the origin of polarity and 
control of cell fate in development. In recent 
years it has become clear that genes that have 
been implicated in human disease play an 
important role in these processes. The goals of 
their research are to improve understanding of 
the mechanisms underlying these key biological 
processes and specifically to gain insight into 
the function of the "disease" genes that have a 
significant influence on human health. The 
current work is focused on the Notch- and the 
Dystroglycan-pathways. In addition, they are 
interested in stem cell division, self-renewal 
and maintenance. In particular, they have 
recently shown that microRNAs regulate stem cell 
division and are now analyzing the key microRNAs 
in the process and investigating their cell cycle 
targets. These basic studies are directed towards 
a long term goal of stem cell based therapeutics.

Dr. Ruohola-Baker is a professor of Biochemistry 
in the School of Medicine at the University of 
Washington.  She received her Ph.D. from Yale 
University in Cell Biology in 1989.

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