[bioundgrd] Fwd: HST NEW Course Offerings

[Janice Chang]

>
>HST.186 Frontiers in (bio)Medical Engineering and Physics
>units: 1-0-2, G-level, graded P/D/F
>M 2-4pm, meets from April 3-May 15, location TBA
>So, here you are in MEMP.  Now what?  This course will provide a 
>framework for 'mapping' research topics at the intersection of 
>medicine and engineering/physics in the Harvard-MIT community and 
>cover the different research areas in MEMP (for example, 
>regenerative biomedical technologies, biomedical imaging and 
>biooptics). Lectures will provide fundamental concepts and also 
>consider what's hot, and why, in each area. In addition, a series of 
>workshops will help students answer the following questions: "How do 
>I turn my interests into a thesis?", "How can I identify a research 
>project that is novel?", "What makes a successful fellowship 
>proposal?", "How do I give and respond to peer reviews?".
>
>S. Bhatia, M. Poe
>HST.186 can be used in place of HST.595 to fulfill the MEMP tutorial 
>requirement.
>
>
>HST.188/9.914 Statistics for Neuroscience Research
>prereq: permission of instructor
>units: 3-0-9, G-level
>MW 9-10.30am, in 46-1015
>A survey introduction to statistical reasoning and statistical 
>methods relevant to neuroscience research. Core topics include 
>introductions to probability theory, estimation theory, hypothesis 
>testing, linear models, the generalized linear model, and 
>experimental design. Additional topics will include Monte Carlo 
>methods, Bayesian methods, time-series analysis, spectral analysis, 
>and point processes theory. Emphasis on developing a firm conceptual 
>understanding of the statistical paradigm and statistical methods 
>primarily through analyses of actual experimental data.   Alternate 
>years.
>E.N. Brown
>
>HST.424J/9.24J Diseases of the Nervous System
>prereq: 9.01
>units: 3-0-9, undergrad
>MW 1-2.30pm, in 46-3310
>This course is intended for undergraduates and graduate students 
>with an interest in neuroscience, bio-medical research and medicine. 
>A wide variety of diseases will be discussed by 
>clinician-scientists, and both clinical presentation and molecular 
>mechanisms of diseases will be presented. Readings will be primarily 
>review and original articles. Topics include: regional functional 
>anatomy of the brain through imaging and stroke; degenerative 
>diseases (Parkinson's, Alzheimer's, ALS); MS; epilepsy; gliomas and 
>CNS stem/precursor cells as they relate to repair mechanisms and 
>cognitive dysfunction following brain radiation therapy and 
>chemotherapy for systemic malignancies. Clinical and pathological 
>findings, differential diagnosis, genetics, pathophysiology and 
>treatment are discussed. There will be two exams during the term 
>plus a final examination.
>T. N. Byrne
>
>
>HST.780 Advanced Speech and Audio Processing (ES257 at Harvard)
>prereq: 6.003 or ES156 or equivalent
>units: 3-0-9 H-level
>time and location TBA
>Introduction to advanced speech and audio processing, including both 
>mathematical models and practical applications thereof. 
>Time-frequency analysis, synthesis, modification, and coding of 
>information-carrying natural sound signals; relevant aspects of 
>acoustics and auditory perception; fundamental contemporary 
>applications and methodologies.  Students are required to prepare a 
>substantial term project at a level on par with current research in 
>the field.  Subject follows Harvard FAS schedule - FAS CLASSES START 
>FEBRUARY 1.
>P. J. Wolfe
>
>HST.854 Evaluating a Biomedical Business Concept
>Prereq: 15.363/HST.971 or permission of instructor
>units: 1-0-2, H-level
>M 12:30-2:30pm, meets from April 3-May 15 in E25-119
>This course will involve critical analysis of new biomedical 
>business ideas. Inventors (largely MIT or Harvard faculty and staff) 
>will present their ideas to the class and provide background 
>material, including scientific papers and patents. A team of 
>students will be assigned to evaluate each business idea. The first 
>question to be asked will be Is there a viable business idea here? 
>If the answer is yes, the students will develop a series of analyses 
>concerning the critical issues that each business idea would face. 
>Issues to be considered might include market opportunity, financing 
>strategies, regulatory hurdles, competitive threats and estimating 
>potential return on investment. Students will be encouraged to 
>review scientific, clinical, patent and marketing literature, as 
>well as to interview key individuals (including the inventors, 
>potential customers and competitors) who can provide useful 
>information.  In each case, analyses will focus on the issues most 
>critical for the success of the proposed business concept.  Analyses 
>will be presented to the entire class.
>R. J. Cohen
>
>HST.987/BE486J Case Studies and Strategies in Drug Discovery and Development
>Prereq: Permission of instructor 
>
>units: 2-0-4, H-Level
>M 3-5pm in 56-614
>The stages in drug discovery and development begin with target 
>identification and end with the submission of preclinical and 
>clinical data to the regulatory authorities. Following 
>identification of a lead compound, there is optimization of 
>structures for pharmaceutical properties, bioavailability, and 
>safety. Subject relies on actual cases of drug development. A major 
>goal is to analyze the cases and determine how the discovery and 
>development process might be influenced by new and future 
>technologies.
>F. L. Douglas, S. R. Tannenbaum, A. J. Sinskey
>
>
>
>
>
>--
>~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
>Domingo B. Altarejos
>Graduate Administrator
>Harvard-MIT Division of Health Sciences and Technology
>Massachusetts Institute of Technology
>77 Massachusetts Avenue
>Building E25, Room 518
>Cambridge, MA  02139-4307
>Tel: (617) 253-3609
>Fax: (617) 253-6692
>http://hst.mit.edu
>~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
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