[Bioundgrd] CI-M option for 7-A majors: 10.28 Bio Engineering Lab
Stu Dietz
dietzs at MIT.EDU
Tue May 3 10:45:27 EDT 2005
>
>Dear Student,
>
>This message is to bring course 10.28 (Biologcal Engineering Lab) to your
>attention for the fall, perhaps especially to those of you majoring in 7A,
>since 10.28 is a Ci-(M) subject (http://web.mit.edu/commreq/cim/course7.html).
>The pre-requisites for 10.28 are 7.02 (or 5.310) and 7.05.
>
>In 10.28 (http://web.mit.edu/10.28/www/) we will cover the complete bioprocess
>design methodology: from the production & separation, to characterization of
>the recombinant product. The two industrial processes we will study are:
>
>* the production of vaccines by animal cell culture
>* the production of recombinant collagen by recombinant E. coli
>
>Students will work in teams through two parallel modules spanning microbial
>fermentation and animal cell culture. With the bioreactor at the core of the
>experiments, students will study cell metabolism and biological pathways,
>kinetics of cell growth and product formation, oxygen mass transport, scale-up
>and techniques for the design of process control loops. Novel bioreactors as
>well as powerful analytical instrumentation will be introduced. Downstream
>processing and recombinant product purification will also be included.
>
>Lectures will be offered throughout the term to present the theory underlying
>the experiments.
>
>As part of the Institute Communication Requirement, recitations on communication are scheduled and will be closely integrated with the technical part of the course. Oral and written presentations will be required as means of enhancing communication skills and receiving constructive criticism in developing new ideas.
>
>If you have any questions on course 10.28, please contact J.-F. Hamel at
>jhamel at mit.edu.
>
>Good luck with the end of term.
>
>J.-F. Hamel
--
Stu Dietz
Biology Education Office, Rm. 68-120
Massachusetts Institute of Technology
77 Massachusetts Ave.
Cambridge, MA 02139
Phone (617) 252-1783
Fax (617) 258-9329
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