[Bioundgrd] Fwd: UROP Project Opening

[Janice Chang]

>
>Fall 2005
>Mechanical Engineering
>Faculty Supervisor: Prof. Peter T.C. So
>
>Single Cell Mechanics
>
>We are interested in hiring 2 UROP students for next year 
>(2005-2006) to carry out experimental work to determine the effect 
>of cell shape on cellular stiffness and cytoskeletal architecture. 
>The size, shape, and location of a single cell is controlled by 
>dropping them on micropatterned islands. Once the cells have adhered 
>and spread on the islands, we perform magnetic trapping experiments 
>to determine their stiffness and use confocal microscopy to 
>visualize cellular structure. Our lab has concluded work involving 
>determining for circular shaped cells the effect of cell size on 
>cellular stiffness and cytoskeletal distribution. Of current 
>interest is, in addition to size, what is the effect of the shape of 
>the cell.
>
>The intent is for each student to conduct experiments for one 
>particular shape and for these results to be included for subsequent 
>publication. We anticipate that this project will take at least one 
>semester but no more than one year to be completed. Estimated 15 
>hrs/week, either for credit or for pay.
>
>Contact: Please send CV to Judith Su 
>(<mailto:judy at mit.edu>judy at mit.edu) by August 19, 2005 for full 
>consideration. After 8/19 the position will remain open until filled.
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