[Bioundgrd] Opportunities at the Broad Institute

[Janice Chang]

>The Broad Institute is a unique research collaboration between MIT, 
>Harvard and its affiliated hospitals, and the Whitehead Institute 
>for Biomedical Research.  The Broad Institute harnesses the 
>intellectual capital of these three outstanding institutions to 
>pioneer applications of genetic research to the understanding and 
>treatment of human diseases such as cancer, multiple sclerosis, and 
>diabetes.
>
>We are seeking a number of talented researchers and engineers at the 
>Bachelor's, Master's and Ph. D. levels to impact research in RNAi 
>Technology, SNP Discovery, Genome Sequencing and Analysis, and 
>Mammalian and Microbial Genetics.
>
>Listed below are open positions relevant for recent graduates.
>
>
>To view complete job descriptions and to apply online, please visit 
>http://web.mit.edu/jobs. Search Keyword: Broad Institute.   EEO.
>
>
>
>Technical Assistant
>
>To apply tools from the Human Genome Project to understand the genetic
>basis of human metabolic and hormonal disorders, e.g., type II diabetes
>and breast cancer. Experiments involve cutting-edge genomic tools (SNP
>genotyping, robotics, high-throughput sequencing) and the application of
>genetic methodologies. Will conduct various bench level experiments and
>basic molecular biology techniques; operate and maintain automated
>laboratory equipment to complete investigations; prepare, order, and
>maintain stocks of necessary reagents, solutions, and supplies;
>document, compile, and analyze data; report data to supervisor and team
>in oral and written reports; attend team meetings to share results, plan
>projects and experiments, and ensure that projects support current team
>goals; assist with calculations and in preparing graphic displays of
>data as part of data analysis; and perform other tasks as requested.
>
>REQUIREMENTS: a bachelor's degree in biology or related field; at least
>one year of experience in a molecular biology laboratory, preferably in
>an independent project; and familiarity with basic molecular biology
>techniques, sterile techniques, and the operation of standard lab
>equipment. Solid knowledge of computers and experience with databases
>required. Excellent communication skills and the ability to interact
>professionally with all levels of staff also required. Must possess
>excellent organization and time management skills and the ability to
>handle a variety of tasks simultaneously. Must be independent and eager
>to work in a fast-paced and dynamic collaborative environment. Comfort
>with fundamental genetic principles and computational approaches a plus.
>(MIT-00001032)
>
>Technical Assistant
>
>To join a group dedicated to the discovery of susceptibility genes for
>common diseases. This group is involved in the development and
>implementation of technologies for disease gene discovery. The work will
>involve a range of techniques for genetic, genomic, and functional
>analyses including sequencing, SNP genotyping, Western and Northern
>analyses, immunohistochemistry, immunoprecipitation, manipulation of
>expression and reporter constructs, and other molecular biology
>techniques. Will perform bench level experiments and computer-based data
>analysis; communicate effectively with all levels of staff to ensure
>that work supports current team goals; conduct bench level experiments
>for genetic, genomic, and functional analyses; operate and maintain
>automated laboratory equipment to complete investigations; prepare,
>order, and maintain stocks of necessary reagents, solutions, and
>supplies; document, compile, and analyze data; report data to supervisor
>and team in oral and written reports; attends team meetings for
>experimental planning; assist with calculations and in preparing graphic
>displays of data as part of data analysis; and perform other tasks as
>needed.
>
>REQUIREMENTS: a bachelor's degree in biology or related field; at least
>one year of experience in a molecular biology laboratory, preferably in
>an independent project; and familiarity with basic molecular biology
>techniques, sterile techniques, and the operation of standard lab
>equipment. Solid knowledge of computers and experience with databases
>required. Excellent communication skills and ability to interact
>professionally with all levels of staff in a fast-paced environment
>required. Excellent organization and time management skills and the
>ability to handle a variety of tasks simultaneously required. (MIT-00001024)
>
>Technical Assistant, (4 positions)
>
>To work on a collaboration with the Whitehead Institute to develop novel
>approaches to RNAi technologies. Will perform RNA biochemistry
>techniques, analyze results, and assist project leaders in applying
>results to develop tools for the study of mammalian genetics.
>
>REQUIREMENTS: a bachelor's degree in biochemistry/biology or related
>field (advanced degree preferred); two years of hands-on laboratory
>experience in DNA/RNA biochemistry/molecular biology; and excellent
>communication, organization, and time management skills. Must be able to
>use sound judgment to handle a variety of tasks and shifting priorities
>and to effectively solve problems. (MIT-00000777)
>
>Data Analyst I, (9 positions)
>
>To perform computer analysis of DNA sequencing projects prior to their
>submission in sequencing databases. Utilizing public sequencing
>databases and sequencing software, will provide final analysis of the
>DNA sequencing projects and experiments initiated in the laboratory by
>the production groups; ensure that projects are properly assembled and
>completed by examining data quality and ordering necessary lab work to
>resolve issues of poor data quality; collaborate with team members to
>allot and prioritize work and to establish team and individual goals
>that support the overall objectives of a high throughput sequencing
>program; and assemble and edit DNA sequences, examine regions of
>sequence for data quality and ambiguity, and implement a variety of
>solutions and novel strategies to resolve regions of poor quality.
>
>REQUIREMENTS: a bachelor's degree, with a concentration or coursework in
>molecular biology or recombinant DNA techniques preferred. Experience
>with NT and Unix environments required. Familiarity with public
>sequencing databases or software preferred. Must be attentive to detail
>and possess an affinity for problem solving. Must be able to work both
>independently and as part of a team. (MIT-00000960)
>
>
>Technical Assistant
>
>To join a high-throughput resequencing and SNP discovery team.
>Responsibilities will include setting up large numbers of PCR reactions
>using robots, quality control of reactions, purification of templates
>for sequencing genotyping, and analysis of sequence data to discover
>SNPs. Will also employ a variety of genomic technologies, including PCR,
>gel electrophoresis and interpretation, and operation of various liquid
>handling devises. The work relies heavily on computer analysis and on a
>variety of genetic methodologies to analyze data, including analysis of
>sequence traces and sequence variant detection.
>
>REQUIREMENTS: a bachelor's degree in chemistry or biology, experience
>with Excel and Netscape, and exceptional written and verbal
>communication and organizational skills. Experience with genomic
>technologies and analysis preferred. Must be able to work well both
>independently as well as part of a team. Ability to juggle several tasks
>at once and thrive in a fast-paced environment necessary. (MIT-00000955)
>
>Technical Assistant
>
>To join a high-throughput resequencing and SNP discovery team.
>Responsibilities will include setting up large numbers of PCR reactions
>using robots, quality control of reactions, purification of templates
>for sequencing genotyping, and analysis of sequence data to discover
>SNPs. Will employ a variety of genomic technologies including PCR, gel
>electrophoresis and interpretation, and operation of various liquid
>handling devises. The work relies heavily on computer analysis and on a
>variety of genetic methodologies to analyze data, including analysis of
>sequence traces and sequence variant detection.
>
>REQUIREMENTS: a bachelor's degree in chemistry or biology and experience
>with Excel and Netscape. Experience with genomic technologies and
>analysis preferred. Must be able to work well both independently and as
>part of a team. Exceptional organizational and written and verbal
>communication skills required. Must be able to juggle several tasks at
>once and thrive in a fast-paced environment.(MIT-00000940)
>
>Technical Assistant
>
>To perform various laboratory techniques and bench level experiments to
>ensure the preparation of high-quality DNA and associated heterozygosity
>testing according to the goals of the mammalian sequencing effort and
>output of high quality genotype data for the Mouse HapMap team. The type
>of techniques employed and the focus of each experiment may vary in
>accordance with shifts in team goals in a dynamic environment.
>
>REQUIREMENTS: a bachelor's degree in biology or related field; at least
>one year of experience in a molecular biology laboratory, preferably on
>an independent project; and familiarity with basic molecular biology
>techniques and the operation of standard lab equipment. Must be familiar
>with programs such as Microsoft Excel and have experience using
>Web-based database. Excellent organization and time management skills
>and the ability to handle a variety of tasks simultaneously required.
>Must be able to exercise sound judgment to align individual work with
>shifts in team goals. (MIT-00000921)