[Bioundgrd] Fwd: BMES Distinguished Lecture Series - January 14th at 7pm

Janice Chang jdchang at MIT.EDU
Fri Jan 9 10:35:17 EST 2004


>
>The Boston chapter of the Institute of Electrical and Electronics Engineers
>         (IEEE)-Engineering in Medicine and Biology Society (EMBS)
>                                  &
>               the MIT Biomedical Engineering Society (BMES)
>                           proudly present:
>
>        *** The 2003-2004 EMBS-BMES Distinguished Lecture Series ***
>
>We invite you to join us for our new monthly lecture series in which we
>explore recent developments and stimulating topics in the expanding field of
>biomedical engineering.  In the fall, speakers from both academia and industry
>will introduce such subjects as genes, genomics, proteomics, and systems
>biology.
>
>Our next lecture will be:
>
>~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
>A massively parallel microfluidics platform for nanovolume storage and ultra-
>high throughput analysis of chemical and biological libraries
>~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
>
>Dr. Tom Morrison
>Senior Director, Genomics
>BioTrove Inc.
>
>Wednesday, January 14th, 2003
>7PM (Refreshments at 6:30PM)
>MIT Building 66, 77 Massachusetts Ave., Room 66-110
>	(For directions to MIT, please visit http://whereis.mit.edu)
>
>* This event is free and open to the public.*
>
>************************************************************************
>
>ABSTRACT:
>
>BioTrove Inc. has developed a novel microfluidic platform, termed the Living
>ChipTM, for nanoliter storage, retrieval and analysis of chemical and
>biological libraries.  Fluid is loaded by capillary action into a precisely
>machined array of up to 24, 576 through-holes in a microtiter plate format
>individually isolated by hydrophobic barriers.  Each through-hole holds up to
>fifty nanoliters of liquid and standard array sizes range from 100 to over
>100,000 through-holes.  Arrays are loaded by dipping into a bath (e.g. reagent
>or cell suspension) or with robotic automation that rapidly transfers fluids
>stored in microtiter plates to an array (nanotiter plate).  Stacking two or
>more nanotiter plates with precisely co-aligned through-holes results in
>mixing of the liquids in opposing channels and subsequent parallel initiation
>of reactions in each through-hole across the array.  For optical-based assays,
>the stack of nanotiter plates is imaged with a CCD camera and custom image
>processing software identifies through-holes containing hits.  An automated
>picker system retrieves and transfers the hits to lower density microtiter
>plates for further analysis.  Results demonstrating homogeneous, inhomogeneous
>and cell-based assays, genomic assays and low-volume, rapid retrieval storage
>of chemical and biological libraries in the nanotiter plate format will be
>presented.
>
>
>
>SPEAKER BACKGROUND:
>
>Dr. Tom Morrison is the Senior Director, Genomics at BioTrove Inc. in Woburn,
>MA.  Prior to BioTrove, Dr. Morrison served as a functional leader for
>Directed Evolution at Genencor International. In this role he hired a five-
>member team to develop and patent novel methods for generating and screening
>biological diversity in microorganisms. Dr. Morrison's accomplishments at
>Genencor include filing multiple pending patent applications and successfully
>improving protease secretion by directed evolution. He also acted as a
>scientific advisor for projects, outside collaborations and new business
>development. Prior to joining Genencor, Tom has published on numerous topics
>in the areas of protein structure and function, host-pathogen interactions and
>embryonic development. Dr. Morrison earned a B.A. in Molecular Biology from
>the University of California at Berkeley and a Ph.D. in Biology from the
>University of Utah.
>
>************************************************************************
>
>If you have any questions, please do not hesitate to contact us.  We look
>forward to seeing you!
>
>
>Best Regards,
>
>Mandy Yeung					Alexis DeSieno
>VP of Special Programs				President
>BMES,	MIT Chapter				BMES, MIT Chapter
>mandyy at mit.edu				alexisd at mit.edu



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