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<p class="MsoNormal"><span style="font-size:15.0pt">There will be a <b><span style="color:red">virtual</span></b><span style="color:red">
</span>Modern Optics and Spectroscopy Seminar held next<b> Tuesday, October 27 at 12pm.
</b>A Q&amp;A segment will immediately follow the conclusion of the seminar.</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">&nbsp;</span><o:p></o:p></p>
<p class="MsoNormal"><b><i><span style="font-size:15.0pt">Zoom link:</span></i></b><o:p></o:p></p>
<p class="p1"><b><span style="font-size:16.0pt;font-family:&quot;Calibri&quot;,sans-serif;color:red"><a href="https://mit.zoom.us/j/93519098713?pwd=RDVpdXNab1hRWVZJR0dqTUQrTWh1Zz09"><span style="color:red">https://mit.zoom.us/j/93519098713?pwd=RDVpdXNab1hRWVZJR0dqTUQrTWh1Zz09</span></a><o:p></o:p></span></b></p>
<p class="MsoNormal"><b><span style="font-size:15.0pt">Passcode: 397855</span></b><o:p></o:p></p>
<p class="MsoNormal"><b><span style="font-size:15.0pt">__________________________</span></b><o:p></o:p></p>
<p class="MsoNormal"><b><span style="font-size:18.0pt">Dan Fu</span></b><b><span style="font-size:17.0pt"><br>
University of Washington</span></b><i><span style="font-size:14.0pt"><br>
<br>
</span></i><b><span style="font-size:18.0pt">“</span></b><b><span style="font-size:18.0pt;color:black">Quantitative chemical imaging of structure and&nbsp;function in living biological samples –
<br>
from single cells to animals</span></b><b><span style="font-size:18.0pt">”</span></b><b><span style="font-size:18.0pt"><o:p></o:p></span></b></p>
<p class="MsoNormal"><br>
<i><span style="color:black">Cell heterogeneity plays a critical role in many pathophysiological processes such as cancer development and neurodegeneration. However, phenotypic variations of individual cells in a complex organ are often intractable by traditional
 analytical techniques. The main obstacles are the limited amount of analyte in a single cell and the need for noninvasive in situ analysis in order to preserve cell&nbsp;function and microenvironmental information. My lab focuses on the development of label-free
 pump-probe microscopy techniques that enables quantitative chemical and&nbsp;functional measurements at high spatial and temporal resolution from cultured cells to living animals. Specifically, we apply high sensitivity stimulated Raman scattering microscopy, an
 emerging chemical imaging tool, to study cell microenvironment and disease processes. We also develop transient absorption microscopy to study a wide range of red blood cell associated&nbsp;functional processes such as neurovascular coupling in mouse brain. Together,
 we aim to build an integrated chemical imaging platform and couple it with advanced data analysis for comprehensive structural and&nbsp;functional imaging of living biological samples at single cell resolution.</span></i><i><o:p></o:p></i></p>
<p class="MsoNormal" style="text-align:justify">&nbsp;<o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">&nbsp;</span><o:p></o:p></p>
<p class="MsoNormal"><b><span style="font-size:11.0pt">Christine Brooks</span></b><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Administrative Assistant</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Massachusetts Institute of Technology</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Department of Chemistry</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">77 Massachusetts Ave, 6-333</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Cambridge, MA 02139</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">p: 617.253.7239</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">e:&nbsp;<a href="mailto:cbrooks@mit.edu">cbrooks@mit.edu</a></span><o:p></o:p></p>
<p class="MsoNormal">&nbsp;<o:p></o:p></p>
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