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<p class="MsoNormal"><span style="font-size:14.0pt">There will be a Modern Optics and Spectroscopy Seminar held
<b>tomorrow, September 24 </b>in <b><a href="http://whereis.mit.edu/?go=34">34-401A</a>
<span style="color:red">at 12pm</span></b></span><o:p></o:p></p>
<p class="MsoNormal"><b><span style="font-size:14.0pt;color:red"> </span></b><b><span style="font-size:14.0pt"> </span></b><o:p></o:p></p>
<p class="MsoNormal"><b><span style="font-size:18.0pt">Haw Yang<br>
Princeton University</span></b><i><span style="font-size:14.0pt"><br>
<br>
</span></i><b><i><span style="font-size:18.0pt">“Real-Time 3D Single-Particle Tracking: Spectroscopy, Imaging, and Control”</span></i></b><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt"> </span><o:p></o:p></p>
<p class="MsoNormal"><i><span style="font-size:13.0pt">Real-time 3D single-particle tracking spectroscopy (RT-3DSPT) is an experimental technique that allows one to follow a nanoscale probe, or a single molecule in special circumstances, as it moves in three-dimensional
space. The probe’s movement could be diffusive or active locomotion. The technique keeps the nano-probe at the center of a microscope objective focus at all times by moving the sample stage to counter any movements that the probe exhibits. Effectively, the
apparatus transforms the experimental coordinate from a lab-based frame to a probe-based frame. This way, it becomes possible to do time-dependent experiments on the probe, or on the molecule tethered to the probe, as if the particle or the molecule is immobilized.
This unconventional experimental approach could enable many interesting research avenues that are not possible before. This presentation will discuss its principle, capabilities and current limitations, as well as new research directions in my laboratory based
on RT-3DSPT—including (1) single-particle spectroscopy, (2) 3D multi-resolution imaging and its application to individual virus-like nanoparticles interacting with a live cell (nano-bio interactions), and (3) steering of self-propelled micro-swimmers.<br>
<br>
</span></i><o:p></o:p></p>
<p class="MsoNormal"> <o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:14.0pt">Refreshments will be served immediately following the seminar!</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
<p class="MsoNormal"><b><span style="font-size:11.0pt">Christine Brooks</span></b><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Administrative Assistant</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Massachusetts Institute of Technology</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Department of Chemistry</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">77 Massachusetts Ave, 6-333</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Cambridge, MA 02139</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">p: 617.253.7239</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">e: <a href="mailto:cbrooks@mit.edu">cbrooks@mit.edu</a></span><o:p></o:p></p>
<p class="MsoNormal"> <o:p></o:p></p>
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