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<p class="MsoNormal"><span style="font-size:14.0pt">There will be a Modern Optics and Spectroscopy Seminar held
<b>next Tuesday, April 23 at 12pm </b>in <b><span style="color:red">5-234</span></b></span><o:p></o:p></p>
<p class="MsoNormal"><b><span style="font-size:14.0pt;color:red"> </span></b><o:p></o:p></p>
<p class="MsoNormal"><b><span style="font-size:14.0pt;color:red">**Please note location**</span></b><o:p></o:p></p>
<p class="MsoNormal"><b><span style="font-size:14.0pt"> </span></b><o:p></o:p></p>
<p class="MsoNormal"><b><span style="font-size:16.0pt">Julie Biteen<br>
University of Michigan</span></b><i><span style="font-size:14.0pt"><br>
<br>
</span></i><b><i><span style="font-size:16.0pt">“</span></i></b><b><i><span style="font-size:16.0pt;color:#333333;background:white">Single-molecule imaging uncovers nanometer-scale fundamentals of cell biology and plasmonics</span></i></b><b><i><span style="font-size:16.0pt">”</span></i></b><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt"> </span><o:p></o:p></p>
<p class="MsoNormal"><i>Our lab has been developing new super-resolution fluorescence microscopy methods to locate, track, and analyze single molecules to answer fundamental, unanswered questions in living bacterial cells. I will discuss how we are measuring
and understanding the dynamical interactions essential for carbohydrate catabolism in the human gut microbiome. Overall, our results provide fundamental insight of relevance to human health and disease.<br>
<br>
</i><i><span style="font-family:"Times New Roman",serif"><o:p></o:p></span></i></p>
<p class="MsoNormal"><i>On the other hand, the resolution of single-molecule bio-imaging is limited by the brightness of fluorescent probes. I will discuss how we are addressing this limitation by taking advantage of the localized surface plasmon resonances
that result from the interaction of light with metal nanoparticles to improve the brightness and photostability of nearby fluorescent labels. We have measured plasmon-enhanced fluorescence one dye at a time in a single-molecule approach that eliminates ensemble
averaging to discover how coupling leads to a predictable shift of the emission position, angle, and polarization.
<o:p></o:p></i></p>
<p class="MsoNormal"><i><br>
<br>
</i><span style="font-size:14.0pt">Refreshments will be served immediately following the seminar!</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
<p class="MsoNormal"><b><span style="font-size:11.0pt">Christine Brooks</span></b><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Administrative Assistant</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Massachusetts Institute of Technology</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Department of Chemistry</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">77 Massachusetts Ave, 6-333</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Cambridge, MA 02139</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">p: 617.253.7239</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">e: <a href="mailto:cbrooks@mit.edu">cbrooks@mit.edu</a></span><o:p></o:p></p>
<p class="MsoNormal"> <o:p></o:p></p>
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