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<p class="MsoNormal"><span style="font-size:14.0pt">There will be a Modern Optics and Spectroscopy Seminar held
<b>TODAY at 12pm </b>in <b><span style="color:red">NE47-189</span></b></span><o:p></o:p></p>
<p class="MsoNormal"><b><span style="font-size:14.0pt;color:red"> </span></b><o:p></o:p></p>
<p class="MsoNormal"><b><span style="font-size:14.0pt;color:red">**Please note location**</span></b><o:p></o:p></p>
<p class="MsoNormal"><b><span style="font-size:14.0pt"> </span></b><o:p></o:p></p>
<p class="MsoNormal"><b><span style="font-size:14.0pt">Daniel A. Heller, Ph.D.</span></b><o:p></o:p></p>
<p class="MsoNormal"><i><span style="font-size:14.0pt">Head, Cancer Nanomedicine Laboratory</span></i><o:p></o:p></p>
<p class="MsoNormal"><i><span style="font-size:14.0pt">Assistant Member, Memorial Sloan Kettering Cancer Center</span></i><o:p></o:p></p>
<p class="MsoNormal"><i><span style="font-size:14.0pt">Assistant Professor, Weill Cornell Medical College, Cornell University</span></i><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:14.0pt"> </span><o:p></o:p></p>
<p class="MsoNormal"><b><i><span style="font-size:14.0pt">“Controlling Carbon Nanotube Photoluminescence for Cancer Research and Diagnosis”
</span></i></b><o:p></o:p></p>
<p class="MsoNormal"><b><i><span style="font-size:14.0pt"> </span></i></b><o:p></o:p></p>
<p class="MsoNormal"><i><span style="font-size:14.0pt">The measurement of biomarkers, drugs, and metabolites in live cells and organisms would allow for improvements in disease detection, drug development, and biomedical research. Single-walled carbon nanotubes
have suitable optical properties for application as sensors for use in live cells and in vivo, including narrow, near-infrared emission bands with sensitivity to the local environment. To develop them into sensors for bioanalytes, we devised new methods to
probe single-walled carbon nanotube optical properties, including near-infrared hyperspectral imaging and live-tissue excitation/emission spectroscopy. We also harnessed a mechanism of carbon nanotube photoluminescence optical bandgap modulation, whereby electrostatic
charges mediate spectral shifts. We believe that this effect is consistent with carbon nanotube solvatochromic behavior and found that this mechanism facilitates the measurement of multiple classes of bioanaltytes, such as nucleic acids, drugs, and proteins,
enabling the development of in vivo implantable sensors for the study and detection of cancer.
</span></i><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><br>
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<p class="MsoNormal">Refreshments will be served immediately following the seminar<o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
<p class="MsoNormal"><b><span style="font-size:11.0pt">Christine Brooks</span></b><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Administrative Assistant</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Massachusetts Institute of Technology</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Department of Chemistry</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">77 Massachusetts Ave, 6-333</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Cambridge, MA 02139</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">p: 617.253.7239</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">e: <a href="mailto:cbrooks@mit.edu">cbrooks@mit.edu</a></span><o:p></o:p></p>
<p class="MsoNormal"> <o:p></o:p></p>
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