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<div><font face="Calibri,sans-serif">Held at </font><b style="font-family: Calibri;">12pm in MIT 34-401, </b><span style="font-family: Calibri;">with lunch served immediately following the talk:</span></div>
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<div style="font-size: 14px; font-family: Calibri;"><span style="font-size: 18px;"><b>Renjie Zhou</b></span></div>
<div style="font-size: 14px; font-family: Calibri;"><span style="font-size: 18px;"><b>Massachusetts Institute of Technology</b></span></div>
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<![endif]--><!--StartFragment--><span style="font-size: 18px;"><b><i>"Tomographic
Phase Microscopy: a label-free platform for 3D imaging of cells"</i></b></span><!--EndFragment--></div>
<div style="font-size: 14px; font-family: Calibri;"><span style="font-size: 16px;"><br>
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<div style="font-size: 14px; font-family: Calibri;"><span style="font-size: 16px;"><br>
</span></div>
<div style="font-size: 14px; font-family: Calibri;"><span style="font-size: 16px;"><i>In this talk, I will first give a brief introduction to quantitative phase microscopy (QPM) and its instrumentation and highlight several important applications. After that,
I will focus my topic on tomographic phase microscopy (TPM), which is a label-free 3D imaging technique based on solving the inverse scattering problem with QPM systems. TPM determines 3D refractive index maps of cells with ~ 500 nm lateral resolution and
~ 1 μm axial resolution. Two types of TPM methods will be discussed in details, namely illumination-angle scanning TPM and coherence-gating TPM. For angle-scanning TPM, I will present our recent progress on pushing the 3D imaging speed by implementing digital
micromirror devices (DMDs). For coherence-gating TPM, I will first review our earlier work on white-light diffraction tomography (WDT), which used the temporal-coherence gating effect to achieve 1 μm depth resolution. While WDT is based on transmission measurements
of forward scattering light, it has the missing cone problem that limited its optical sectioning capability for flat samples. This issue can be mitigated by developing a coherence-gating reflection TPM based on using a spatially incoherent dynamic laser speckle
illumination. I will share our recent efforts towards accomplishing such a system before my talk comes to the end. </i></span></div>
<div style="font-size: 14px; font-family: Calibri;"><span style="font-size: 16px;"><br>
</span></div>
<div style="font-size: 14px; font-family: Calibri;">Renjie Zhou is a postdoctoral associate at George R. Harrison Spectroscopy Laboratory at MIT, where his research centers on developing sensitive interferometric microscopy systems and high throughput 3D imaging
methods for biomedical applications. Dr. Zhou received PhD in Electrical and Computer Engineering from the University of Illinois at Urbana-Champaign (UIUC) in 2014. His dissertation focused on developing wafer defect inspection instruments and solving 3D
inverse scattering problems for cell imaging. Dr. Zhou has co-authored over 40 peer-reviewed journal and conference papers. He has received a number of research awards including the Arnold Beckman Fellowship from the Beckman Institute, Scholarship in Optics
& Photonics and Newport Spectra - Physics Research Excellence Travel Grant from SPIE; Jean Bennett Memorial Student Travel Grant finalist from OSA; P. D. Coleman Outstanding Research Award and Yuen T. Lo Outstanding Graduate Research Award from UIUC. He is
avid in promoting optical sciences. </div>
</div>
<div style="font-size: 14px; font-family: Calibri;"><br>
</div>
<div style="font-size: 14px; font-family: Calibri, sans-serif;">
<div id="">
<div><b style="font-family: Tahoma;">Christine Brooks</b></div>
<div>Administrative Assistant</div>
<div>Massachusetts Institute of Technology</div>
<div>Department of Chemistry</div>
<div>77 Massachusetts Ave, 6-333</div>
<div>Cambridge, MA 02139</div>
<div>p: 617.253.7239</div>
<div>e: <a href="mailto:cbrooks@mit.edu">cbrooks@mit.edu</a></div>
<div><br>
</div>
</div>
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