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<span style="font-size: 14px;"><b>Lester Wolfe Workshop in Laser Biomedicine</b><b><o:p></o:p></b></span></p>
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<b style="font-size: 14px;"> </b><b style="font-size: 14px;"> </b></p>
<p class="MsoBodyText" style="text-align: center;"><span style="font-size: 14px;">“Probing single molecules with light”<o:p></o:p></span></p>
<p class="MsoBodyText" style="text-align: center;"><font size="2"> <b style="text-align: center;"> </b><span style="color: blue;">It has long been a goal of scientists to be able to investigate molecular interactions at the single molecule level. Biological
interactions are often weak and transitory in nature and need extremely sensitive techniques to be able to detect single molecules. The Fall Lester Wolfe Workshop will present instances in which the power and precision of light can be harnessed to “see” single
molecules</span><b> </b></font></p>
<p class="MsoNormal" style="text-align: center;"><b><font size="2"> </font></b></p>
<p class="MsoNormal" style="text-align: center;"><b><font size="2"> </font></b></p>
<p class="MsoNormal" style="text-align: center;"><b><font size="2">A pre-transcriptional regulation mechanism predicts gene expression output in living cells<o:p></o:p></font></b></p>
<p class="MsoNormal" style="text-align: center;"><i><font size="2">Ibrahim Cisse, Massachusetts Institute of Technology<o:p></o:p></font></i></p>
<p class="MsoNormal" style="text-align: center;"><b><font size="2"> </font></b></p>
<p class="MsoNormal" style="text-align: center;"><b><font size="2">Spontaneous motions of DNA and protein probed with single molecule methods<o:p></o:p></font></b></p>
<p class="MsoNormal" style="text-align: center;"><i><font size="2">Tae-Hee Lee, Pennsylvania State University<o:p></o:p></font></i></p>
<p class="MsoNormal" style="text-align: center;"><b><font size="2"> </font></b></p>
<p class="MsoNormal" style="text-align: center;"><b><font size="2">Mechanical forces in nanoscale biology: from hemostasis to single-molecule centrifugation<o:p></o:p></font></b></p>
<p class="MsoNormal" style="text-align: center;"><font size="2"><i>Wesley Wong, Harvard University</i> </font></p>
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<div style="text-align: center;"><font size="2"><br>
</font></div>
<h1 style="text-align: center;"><span style="font-weight: normal;"><font size="2">Tuesday, October 20, 2015, 4:00-6:00 PM<o:p></o:p></font></span></h1>
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<b><font size="2">Massachusetts Institute of Technology<o:p></o:p></font></b></p>
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<font size="2">Grier Room, 34-401<o:p></o:p></font></p>
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<font size="2">77 Massachusetts Avenue, Cambridge<o:p></o:p></font></p>
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<font size="2"> </font></p>
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<font size="2">Refreshments served at 3:30 PM<o:p></o:p></font></p>
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<font size="2"> </font></p>
<p class="MsoNormal" align="center" style="text-align:center"><font size="2"><span style="font-family: 'Times New Roman';">Sponsored by the MIT Laser Biomedical Research Center, Chemistry Department, MIT;
</span><span style="font-family: 'Times New Roman'; letter-spacing: -0.2pt;">MGH Wellman Center for Photomedicine; Harvard—MIT Division of Health Sciences and Technology</span></font><span style="font-size:11.0pt;font-family:"Times New Roman";mso-fareast-font-family:
"Times New Roman""><o:p></o:p></span></p>
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