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<!--StartFragment--><p class="MsoTitle" style="margin-right:-.5in"><font class="Apple-style-span" face="'Times New Roman'"><b><br></b></font></p><p class="MsoTitle" align="left" style="margin-right:-.5in;text-align:left"><b style="mso-bidi-font-weight:normal"><span style="font-size:8.0pt;mso-bidi-font-size:
12.0pt;font-family:"Times New Roman""><o:p> </o:p></span></b></p><p class="MsoTitle" style="margin-right:-.5in"><b style="mso-bidi-font-weight:
normal"><span style="font-size:8.0pt;mso-bidi-font-size:12.0pt;font-family:
"Times New Roman""><o:p> </o:p></span></b></p><p class="MsoNormal" align="center" style="text-align:center"><font class="Apple-style-span" size="4"><b style="mso-bidi-font-weight:
normal"><span style="letter-spacing: 1.5pt; ">Modern Optics and Spectroscopy</span></b><span style="font-family:Arial;
letter-spacing:1.5pt"><o:p></o:p></span></font></p><p class="MsoNormal" align="center" style="text-align:center"><b style="mso-bidi-font-weight:
normal"><span style="font-family: Arial; letter-spacing: 1pt; "><o:p><font class="Apple-style-span" size="4"> </font></o:p></span></b></p><p class="MsoNormal" align="center" style="margin-right:-13.5pt;text-align:center"><b style="mso-bidi-font-weight:normal"><i style="mso-bidi-font-style:normal"><font class="Apple-style-span" size="4">Optical biosensors and
systems integration</font></i></b></p><p class="MsoNormal" align="center" style="text-align:center"><font class="Apple-style-span" size="4"><b style="mso-bidi-font-weight:
normal">Frances S.
Ligler</b><span style="letter-spacing: 1pt; ">,<o:p></o:p></span></font></p><p class="MsoNormal" align="center" style="text-align:center"><span style="letter-spacing: 1pt; "><font class="Apple-style-span" size="4">Naval
Research Laboratory, Washington D.C.<o:p></o:p></font></span></p><p class="MsoNormal" align="center" style="text-align:center"><span style="letter-spacing: 1pt; "><o:p><font class="Apple-style-span" size="4"> </font></o:p></span></p><p class="MsoNormal" align="center" style="text-align:center"><span style="letter-spacing: 1pt; "><font class="Apple-style-span" size="4">Tuesday,
October 9, 2012</font></span></p><p class="MsoNormal" align="center" style="text-align:center"><span class="Apple-style-span" style="letter-spacing: 1px; font-size: large; ">12:00 –
1:00 p.m.</span></p><p class="MsoNormal" align="center" style="text-align:center"><font class="Apple-style-span" face="Arial" size="4"><span class="Apple-style-span" style="letter-spacing: 1px;"><br></span></font></p><p class="MsoNormal" style="text-align:justify"><font class="Apple-style-span" size="4">New
concepts for molecular recognition, integration of microfluidics and optics,
simplified fabrication technologies, and improved approaches to biosensor
system integration are producing smaller, faster, cheaper biosensors with
capacity to provide effective and actionable information.<span style="mso-spacerun:yes"> </span>We have combined microfluidic mixers,
magnetic field control, and hydrodynamic focusing methods to move target
molecules and cells into a variety of optical interrogation devices.<span style="mso-spacerun:yes"> </span>These approaches achieve improved target
delivery to sensors and reduced clogging.<span style="mso-spacerun:yes">
</span>Most importantly, we have focused on issues critical for effective
systems integration, including the interactivity of the choices for sampling
technology, biochemistry, optics, fluidics, and electronics.<span style="mso-spacerun:yes"> </span>The overall sensing geometry, size, power,
and data readout must address the sensing needs and the user requirements—in a
final format that is as simple, robust, and inexpensive as possible.<span style="mso-spacerun:yes"> </span><o:p></o:p></font></p><p class="MsoNormal" style="text-align:justify"><o:p><font class="Apple-style-span" size="4"> </font></o:p></p><p class="MsoNormal" style="text-align:justify"><o:p><font class="Apple-style-span" size="4"> </font></o:p></p><p class="MsoNormal" align="center" style="text-align:center"><font class="Apple-style-span" size="4">Grier Room, MIT Bldg 34-401<o:p></o:p></font></p><p class="MsoNormal" align="center" style="text-align:center"><font class="Apple-style-span" size="4">Refreshments served after
the lecture</font><font class="Apple-style-span" size="6"><o:p></o:p></font></p>
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