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--></style><title>Lester Wolfe Workshop
4/20/2010</title></head><body>
<div align="center"><font face="Geneva" size="+1"
color="#000000"><b>Lester Wolfe Workshop in Laser
Biomedicine</b></font></div>
<div align="center"><font face="Geneva" size="+1"
color="#000000"><b>Optogenetics - Probing the Brain with
Light</b></font></div>
<div align="center"><font face="Geneva" size="+1"
color="#000000"><b><br></b></font></div>
<div align="center"><font face="Geneva" color="#000000">This
Lester-Wolfe Workshop covers a relatively new, but already a
highimpact</font></div>
<div align="center"><font face="Geneva" color="#000000">field called
Optogenetics. It is concerned with the use of</font></div>
<div align="center"><font face="Geneva" color="#000000">genetically
encoded light-sensitive proteins like channel rhodopsins
and</font></div>
<div align="center"><font face="Geneva" color="#000000">high-speed
optical methods for probing and controlling specifically</font></div>
<div align="center"><font face="Geneva" color="#000000">targeted
neurons within intact neural circuits. Light can be delivered
at</font></div>
<div align="center"><font face="Geneva" color="#000000">will to switch
on or off specific groups of neurons thus providing
answers</font></div>
<div align="center"><font face="Geneva" color="#000000">to fundamental
questions in neurobiology.</font></div>
<div align="center"><font face="Geneva" size="+1"
color="#000000"><br></font></div>
<div><font face="Geneva" size="+1" color="#000000"><b>Optogenetics -
Engaging the Brain Microcircuits with Light</b></font></div>
<div><font face="Geneva" size="+1" color="#000000"><i><b>Arto
Nurmikko</b>, Brown University</i></font></div>
<div><font face="Geneva" size="+1"
color="#000000"><i><br></i></font></div>
<div><font face="Geneva" size="+1" color="#000000"><b>Engineering
Light-gated Neurotransmitter Receptors</b></font></div>
<div><font face="Geneva" size="+1" color="#000000"><i><b>Stephanie
Szobota</b>, University of California, Berkeley</i></font></div>
<div><font face="Geneva" size="+1"
color="#000000"><i><br></i></font></div>
<div><font face="Geneva" size="+1" color="#000000"><b>Optical
Deconstruction of Sleep-wake Circuits in the Brain</b></font></div>
<div><font face="Geneva" size="+1" color="#000000"><i><b>Antoine
Adamantidis</b>, Stanford University</i></font></div>
<div><font face="Geneva" size="+1"
color="#000000"><i><br></i></font></div>
<div><font face="Geneva" size="+1" color="#000000"><b>A New View of
Neocortical Function: Integration of Optogenetic</b></font></div>
<div><font face="Geneva" size="+1" color="#000000"><b>Control with
High-resolution fMRI</b></font></div>
<div><font face="Geneva" size="+1" color="#000000"><i><b>Itamar
Kahn</b>, Harvard University</i></font></div>
<div><font face="Geneva" size="+1"
color="#000000"><i><br></i></font></div>
<div align="center"><font face="Geneva" size="+1"
color="#000000"><b>Tuesday, April 20, 2010</b></font></div>
<div align="center"><font face="Geneva" size="+1"
color="#000000"><b>4:00 - 6:00 PM (Coffee 3:30PM)</b></font></div>
<div align="center"><font face="Geneva" size="+1"
color="#000000"><b>Massachusetts General Hospital</b></font></div>
<div align="center"><font face="Geneva" size="+1"
color="#000000"><b>Richard B. Simches Research Center, Room
3110</b></font></div>
<div align="center"><font face="Geneva" size="+1"
color="#000000"><b>185 Cambridge Street, Boston</b></font></div>
<div align="center"><font face="Geneva" size="+1"
color="#000000"><b>(located in Charles River Plaza next to Whole Foods
Market and CVS)</b></font></div>
<div align="center"><font face="Geneva" color="#000000">Sponsored by
the G. R. Harrison Spectroscopy Laboratory, MIT; MGH Wellman Center
for</font></div>
<div align="center"><font face="Geneva" color="#000000">Photomedicine;
Harvard-MIT Division of Health Sciences and Technology; and CIMIT
(Center for Integration</font></div>
<div align="center"><font face="Geneva" color="#000000">of Medicine
and Innovative Technology).</font></div>
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