<!doctype html public "-//W3C//DTD W3 HTML//EN">
<html><head><style type="text/css"><!--
blockquote, dl, ul, ol, li { padding-top: 0 ; padding-bottom: 0 }
--></style><title>April 6, 2010</title></head><body>
<div align="center"><font face="Times New Roman"
color="#000000"><b>Seminar on</b></font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><b><br></b></font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><b>Modern Optics and Spectroscopy</b></font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><b><br></b></font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><i><b>Breasts and brains, similarities and
differences: Understanding the basic science behind Optical
Molecular imaging</b></i></font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><i><b><br></b></i></font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><b>Warren Warren</b>,</font></div>
<div align="center"><font face="Times New Roman" color="#000000">Duke
University</font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><br></font></div>
<div align="center"><font face="Times New Roman"
color="#000000">Tuesday, April 6, 2010</font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><br></font></div>
<div align="center"><font face="Times New Roman" color="#000000">12:00
- 1:00 p.m.</font></div>
<div align="center"><font face="Times"
color="#000000"><br></font></div>
<div align="center"><font face="Times New Roman"
color="#000000">Conventional clinical imaging methods, such as MRI or
X-rays, are good at measuring structure but not function, and thus are
often useless for early diagnosis of disease. Molecular imaging-the
use of localized chemical signatures-is a rapidly expanding field
which fuses chemistry, physics, and engineering to enable a revolution
in medical practice. I will discuss a variety of applications
(focusing largely on our work with nonlinear optical methods, with
some context provided by magnetic resonance) which illustrate this
fusion. For example, we have developed the technology to
"sculpt" ultrafast laser pulses in time, thus letting us
image molecular singatures other than fluorescence-for example,
stimulated emission, sum frequency absorption, and self phase
modulation. We will discuss applications to hemoglobin, melanins
and other molecules to diagnose skin cancer; to imaging neuronal
firing; and to high resolution stimulated Raman microscopy. The
ultimate goal is to develop enhancements to the radiologist's
"tool kit" which save lives, reduce medical costs, and
improve public health.</font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><br></font></div>
<div align="center"><font face="Times New Roman" color="#000000">Grier
Room, MIT Bldg 34-401</font></div>
<div align="center"><font face="Times New Roman"
color="#000000">Refreshments served after the lecture</font></div>
</body>
</html>