<!doctype html public "-//W3C//DTD W3 HTML//EN">
<html><head><style type="text/css"><!--
blockquote, dl, ul, ol, li { padding-top: 0 ; padding-bottom: 0 }
--></style><title>March 24, 2009</title></head><body>
<div align="center"><font face="Times New Roman"
color="#000000"><b>Seminar on</b></font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><b><br></b></font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><b>Modern Optics and Spectroscopy</b></font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><b><br></b></font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><i><b>Detecting cervical dysplasia with quantitative
spectroscopic imaging</b></i></font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><i><b><br></b></i></font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><b>Condon Lau</b>, MIT</font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><br></font></div>
<div align="center"><font face="Times New Roman"
color="#000000">Tuesday, March 24, 2009</font></div>
<div align="center"><font face="Times New Roman" color="#000000">Grier
Room 34-401</font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><br></font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><br></font></div>
<div align="center"><font face="Times New Roman" color="#000000">12:00
- 1:00 p.m.</font></div>
<div align="center"><font face="Times"
color="#000000"><br></font></div>
<div align="center"><font face="Times New Roman" color="#000000">We
use Quantitative Spectroscopic Imaging (QSI) to study patients
referred for colposcopy or Loop Electrosurgical Excision Procedure to
identify high-grade squamous intraepithelial lesions (HSIL) in
cervical transformation zone. To accomplish this, we normalize
spectroscopy measurements and utilize the spatial continuity of HSIL
to improve accuracy. Results from the study show that sites determined
to be HSIL by QSI are in good agreement with pathology. Furthermore,
the diagnostic criteria are independent of instrumentation. QSI can
improve early cancer detection in the cervix and has the potential to
be inexpensiveand easy to use, making it suitable for applications in
developed and developing countries.</font></div>
<div align="center"><font face="Times New Roman"
color="#000000"><br></font></div>
<div><font face="Times New Roman" size="+2"
color="#000000"><br></font></div>
<div><font face="Times New Roman" size="+2"
color="#000000"><br></font></div>
</body>
</html>