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<div><font face="Times New Roman" size="+3" color="#000000"><b>Lester
Wolfe Workshop in Laser Biomedicine<br>
<br>
</b></font><font face="Times New Roman" size="+5"
color="#000000"><b>Optical Imaging of Pre-Cancer in the Esophagus<br>
</b></font><font face="Times New Roman" size="+3"
color="#000000"><b>Tuesday, April 12, 2005, 4:00-6:00 PM<br>
Massachusetts General Hospital<br>
Wellman 1 Conference Room<br>
50 Blossom Street, Boston<br>
<br>
</b></font><font face="Times New Roman" size="+2" color="#000000">The
incidence of cancer of the esophagus is increasing rapidly in the
Western world. Chronic gastroesophageal reflux disease leads to a
premalignant change in the esophageal epithelium, known as Barrett's
esophagus, and this can progress to dysplasia and adenocarcinoma. The
traditional method of detecting these changes employs endoscopy and
taking of multiple biopsies. This workshop will discuss non-invasive
optical methods of detecting and monitoring esophageal precancer,
including optical coherence tomography, tri-modal spectroscopy and
endoscopic confocal microscopy.<br>
<br>
<br>
<b>Screening and Surveillance of Barrett's Esophagus: The Challenge,
Current Status and Opportunities<br>
</b><i>Norman Nishioka, Massachusetts General Hospital and Harvard
Medical School<br>
</i><b>Upper Gastrointestinal Optical Coherence Tomography<br>
</b><i>Brett Bouma, Massachusetts General Hospital and Harvard Medical
School<br>
</i><b>Real-Time Spectral Diagnosis of Dysplasia in Barrett's
Esophagus<br>
</b><i>James Tunnell, MIT Spectroscopy Laboratory<br>
<br>
</i><b>Endoscopic Confocal Microscopy for Structure and Function<br>
</b><i>Gordon Kino, Stanford University<br>
<br>
<br>
</i>Refreshments served at 3:30 PM<br>
<br>
Sponsored by the G.R. Harrison Spectroscopy Laboratory, MIT, MGH
Wellman Laboratories, the Harvard-MIT Division of Health Sciences and
Technology, and the Center for the Integration of Medicine and
Innovative Technology<br>
<br>
(Map available online at<u>
http://www.cimit.org/images/MGH_Map011305.pdf</u>)</font></div>
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