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<font face="Palatino"><span style="font-size:12pt">Alnylam Pharmaceuticals is a well-established, mid-sized biotechnology company located in Cambridge, MA pioneering the translation of siRNA into a new class of therapeutics. We are looking for a well-developed post-doc/immunologist to drive our immune stimulation platform efforts within our lead optimization organization. With one tech, the Immunoassay Development lead will adopt and optimize existing screens, and do follow on in vivo work in order to evolve the overall platform. An understanding of innate immunity would be ideal, but it not required; the ability to leverage the literature and collaborations to elucidate a complex area as we work toward systemic delivery of siRNA is a must. Top-notch publications, great interpersonal skills, outstanding presentation skills are key. Most of all, we need a true contributor who has significant cell-based screening experience.<br>
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<b>Immunoassay Development Lead – RNAi Lead Development<br>
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The RNAi Lead Development (RLD) Team is seeking a highly motivated cellular immunologist with proven abilities in the development, design, execution, supervision, analysis, interpretation, and communication of immunology <i>in vitro</i> and <i>in vivo</i> assays in a screening environment. The Immunoassay Development (IAD) Lead will develop, optimize, and implement medium to high throughput oligonucleotide-based immunoassays to screen a variety of candidate RNAi compounds and delivery modalities and manage a significant volume of <i>in vitro</i> cell biology activities<br>
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<b>Responsibilities include:<br>
</b></span></font><span style="font-size:12pt"><font face="Symbol">· </font><font face="Palatino">Strategic planning and coordination of activities<br>
</font><font face="Symbol">· </font><font face="Palatino">Management of junior staff<br>
</font><font face="Symbol">· </font><font face="Palatino">Hands-on assay development and execution<br>
</font><font face="Symbol">· </font><font face="Palatino">Literature review<br>
</font><font face="Symbol">· </font><font face="Palatino">Timely delivery of presentations<br>
The individual will work closely with multiple project teams across various therapeutic areas. <br>
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</font></font><font face="Palatino">The successful candidate will be expected to establish top-notch collaboration(s) with the goals of augmenting existing resources in support of various projects and partnerships and driving provocative, highly publishable research.<br>
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<b>Key Requirements<br>
</b></font><font face="Symbol">· </font><font face="Palatino">Ph.D. in Immunology (<b><u>highly</u></b> preferred), or a related field.<br>
</font><font face="Symbol">· </font><font face="Palatino">At least six years experience in immunoassay development and tissue culture.<br>
</font><font face="Symbol">· </font><font face="Palatino">Expertise in in vivo modeling is highly desirable.<br>
</font><font face="Symbol">· </font><font face="Palatino">Knowledge of methods such as ELISA, ELISpot, FACS analysis, taqman and PBMC assays is required.<br>
</font><font face="Symbol">· </font><font face="Palatino">Experience with medium to high throughput screening and automation preferred.<br>
</font><font face="Symbol">· </font><font face="Palatino">Superior communication, organization, follow-through, and presentations skills are a must. <br>
To apply, please visit www.alnylam.com/careers <<font color="#0000FF"><u><a href="http://www.alnylam.com/careers">http://www.alnylam.com/careers</a></u></font>> and apply directly to the position.<br>
Alnylam Pharmaceuticals is an AA/EEO employer committed to an exciting, diverse, and enriching work environment.<br>
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</span><span style="font-size:12pt">*****************************************<br>
Debra L. Martin, Programs Manager<br>
MIT<br>
Vice President for Research Office, Room 11-268<br>
77 Massachusetts Avenue<br>
Cambridge, MA 02139<br>
617-258-0310, 617-252-1003 (fax)<br>
<a href="debra@mit.edu">debra@mit.edu</a><br>
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