<!doctype html public "-//W3C//DTD W3 HTML//EN">
<html><head><style type="text/css"><!--
blockquote, dl, ul, ol, li { padding-top: 0 ; padding-bottom: 0 }
--></style><title>Alnylam Pharmaceuticals Biochemist
position</title></head><body>
<div>FYI</div>
<div><br></div>
<blockquote type="cite" cite><br></blockquote>
<blockquote type="cite" cite><br></blockquote>
<blockquote type="cite" cite><font face="Arial" size="-1"><b>Alnylam
Pharmaceuticals</b></font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial"
size="-1"><b>Cambridge, Massachusetts</b><br>
<b>Scientist, Biochemistry</b></font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial"> </font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial">We seek a talented
Biochemist to join our interdisciplinary team to design and execute
various biochemical and molecular biological experiments with a goal
to develop a new siRNA delivery platform. </font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial"> </font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial">Primary
responsibilities:</font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial"> </font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial">§<font
size="-1"> </font>
Design and perform various biochemical assays to optimize protein
reconstitution.</font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial"> </font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial">§<font
size="-1"> </font>
Plan, set up, and perform biochemical and cell assays to evaluate
conjugates with different formulations.</font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial"> </font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial">§<font
size="-1"> </font> Help
design and manage external (CRO) and internal studies on protein
expression in mammalian cells and E. coli, and protein
purification.</font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial"> </font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial">§<font
size="-1"> </font>
Perform protein engineering to improve or modify the function of
proteins.</font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial"> </font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial">§<font
size="-1"> </font>
Partner with delivery and formulation teams.</font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial"> </font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial">Requirements include a
PhD in Biochemistry, Chemistry or Biology with solid biochemistry and
molecular biology experience. Experience in protein
reconstitution, protein expression and purification, protein chemistry
or quantitative analysis of cell-surface receptor-ligand is required.
Experience in FPLC, RT-PCR, density gradient ultracentrifugation or
cell culture is a plus. The candidate must be flexible to be
able to apply his/her knowledge to new areas of study and possess
excellent communication skills.</font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial"> </font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial"> </font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial">To apply, please send
your resume to hr@alnylam.com</font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial"> </font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial">Alnylam
Pharmaceuticals is committed to a diverse workplace. </font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite><font face="Arial"> </font><br>
<font face="Arial" size="-1"></font></blockquote>
<blockquote type="cite" cite> <br>
<font face="Arial" size="-2" color="#666666"></font></blockquote>
<blockquote type="cite" cite><font face="Arial" size="-2"
color="#666666"
>__________________________________________________________</font><br>
<font face="Arial" size="-2" color="#666666"></font></blockquote>
<blockquote type="cite" cite><font face="Verdana" size="-1"
color="#008080">Michael Andolino | Principal Recruiting
Consultant </font><br>
<font face="Verdana" size="-2" color="#999933"></font></blockquote>
<blockquote type="cite" cite><font face="Verdana" size="-2"
color="#999933"> </font><br>
<font face="Verdana" size="-2" color="#999933"></font></blockquote>
<blockquote type="cite" cite><font face="Arial" size="-2"
color="#666666"><b>Alnylam Pharmaceuticals | 300 Third
Street, Cambridge, MA 02142</b></font><br>
<font face="Verdana" size="-2" color="#999933"></font></blockquote>
<blockquote type="cite" cite><font face="Arial" size="-2"
color="#666666"><b>Direct: 617 551 8228 | Fax:
617 551 8101 |</b></font> <a
href="http://www.alnylam.com/"><font face="Arial" size="-2"
color="#666666"><b>www.alnylam.com</b></font></a></blockquote>
<div><br></div>
<div><br></div>
<x-sigsep><pre>--
</pre></x-sigsep>
<div>************************************<br>
Debra L. Martin, Programs Manager<br>
MIT<br>
Vice President for Research Office, 11-268<br>
77 Massachusetts Avenue<br>
Cambridge, MA 02139<br>
617-258-0310, 617-252-1003 (fax)<br>
debra@mit.edu</div>
</body>
</html>