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<DIV><FONT face=Arial size=2>Hi Karen,</FONT></DIV>
<DIV><FONT face=Arial size=2></FONT> </DIV>
<DIV><FONT face=Arial size=2>could you do me a huge favor and forward this
e-mail to <A href="mailto:csbi-events@mit.edu">csbi-events@mit.edu</A> asap (if
you receive this after 3pm, it is not necessary)</FONT></DIV>
<DIV><FONT face=Arial size=2></FONT> </DIV>
<DIV><FONT face=Arial size=2>Thanks, ALexander.</FONT></DIV>
<DIV><FONT face=Arial size=2></FONT> </DIV>
<DIV style="FONT: 10pt arial">_____________________________________<BR></DIV>
<DIV class=Section1>
<DIV>
<P class=MsoNormal><B><FONT face="Times New Roman" size=3><SPAN
style="FONT-WEIGHT: bold; FONT-SIZE: 12pt">Reminder:
Today!<o:p></o:p></SPAN></FONT></B></P>
<P class=MsoNormal><FONT face="Times New Roman" size=3><SPAN
style="FONT-SIZE: 12pt"><o:p> </o:p></SPAN></FONT></P>
<P class=MsoNormal><FONT face="Times New Roman" size=3><SPAN
style="FONT-SIZE: 12pt">Fall 2007 Seminar Series on Computational and Systems
Biology<o:p></o:p></SPAN></FONT></P>
<P class=MsoNormal><FONT face="Times New Roman" size=3><SPAN
style="FONT-SIZE: 12pt">Friday, November 30, 2007<o:p></o:p></SPAN></FONT></P>
<P class=MsoNormal><FONT face="Times New Roman" size=3><SPAN
style="FONT-SIZE: 12pt">3:00pm - 4:00pm<o:p></o:p></SPAN></FONT></P>
<P class=MsoNormal><FONT face="Times New Roman" size=3><SPAN
style="FONT-SIZE: 12pt">Room 4-370<o:p></o:p></SPAN></FONT></P>
<P class=MsoNormal><FONT face=Garamond size=3><SPAN
style="FONT-SIZE: 12pt; FONT-FAMILY: Garamond"><o:p> </o:p></SPAN></FONT></P>
<P class=MsoNormal><FONT face="Times New Roman" size=3><SPAN
style="FONT-SIZE: 12pt">Presenting:<BR><B><SPAN style="FONT-WEIGHT: bold">Dr.
Pamela Silver</SPAN></B><BR><I><SPAN style="FONT-STYLE: italic">Department of
Systems Biology/Harvard Medical School<o:p></o:p></SPAN></I></SPAN></FONT></P>
<P class=MsoNormal><FONT face="Times New Roman" size=3><SPAN
style="FONT-SIZE: 12pt"><BR><U>Title:</U> <B><I><SPAN
style="FONT-WEIGHT: bold; FONT-STYLE: italic">Designing Biological
Systems</SPAN></I></B><BR><U>Abstract:</U> Biology presents us with an array of
design principles. We are interested in using the foundations of
biology to engineer cells in a logical way to perform certain functions. In
doing so, we learn more about the fundamentals of biological design as well as
engineer useful devices with a myriad of applications. For example, we are
interested in combining transcription-based with post-transcriptional logic such
as protein localization and degradation to build cells that can perform specific
tasks, such as counting mitotic divisions, measuring life span and remembering
past events. I will discuss the successful design and construction
of aeukaryotic system with predictable biological properties as well as a novel
synthetic protein platform for altering cell behavior. I will also discuss
the logical design of bio-systems for regulation of metabolic
pathways.<BR><BR>Light refreshments to be served at 2:45 p.m.<BR><BR>Host:
Dr. Alexander van Oudenaarden<BR>Department of
Physics<BR>_______________________________________________<BR>CSBi-events
mailing list<BR>CSBi-events@mit.edu</SPAN></FONT><FONT face=Arial size=2><SPAN
style="FONT-SIZE: 10pt; FONT-FAMILY: Arial"><BR></SPAN></FONT><SPAN
class=MsoHyperlink><U><FONT
color=blue>http://mailman.mit.edu/mailman/listinfo/csbi-events</FONT></U></SPAN><o:p></o:p></P></DIV></DIV></BODY></HTML>