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<p class="MsoNormal"><span style="font-family:"Calibri",sans-serif;color:#212121">Dear Students,</span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-family:"Calibri",sans-serif;color:#212121"> </span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-family:"Calibri",sans-serif;color:#212121">The biology department is offering new subjects for 2024-2025. We'd like to highlight the following new subjects below.</span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-family:"Calibri",sans-serif;color:#212121"> </span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-family:"Calibri",sans-serif;color:#212121"><a href="https://student.mit.edu/catalog/index.cgi" title="https://student.mit.edu/catalog/index.cgi"><span style="color:#0078D7">https://student.mit.edu/catalog/index.cgi</span></a></span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-family:"Calibri",sans-serif;color:#212121"> </span><span style="color:#212121"><o:p></o:p></span></p>
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<b><span style="font-family:"Calibri",sans-serif;color:#212121">FALL 2024</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-family:"Calibri",sans-serif;color:#212121"> </span><span style="color:#212121"><o:p></o:p></span></p>
<p class="MsoNormal" style="caret-color: rgb(33, 33, 33);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-stroke-width: 0px;word-spacing:0px">
<b><span style="font-family:"Calibri",sans-serif;color:#212121">7.36/7.91</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<b><span style="font-family:"Calibri",sans-serif;color:#212121">The CRISPR revolution: Engineering the Genome for Basic Science and Clinical Medicine</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<b><span style="font-family:"Calibri",sans-serif;color:#212121">Faculty: Francisco Sanchez-Rivera, Jonathan Weissman</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<b><span style="font-family:"Calibri",sans-serif;color:#212121">TR11:30-1</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-size:9.0pt;font-family:"Verdana",sans-serif;color:#333333;background:white">Provides a conceptual and technical understanding of genome editing systems and their research and clinical applications. Focuses on fundamental CRISPR biology in
bacteria, methodologies for manipulating the genome with CRISPR, and the application of genome engineering in research and medicine. Combines lectures and literature discussions with critical analysis and assigned readings, with the goal of better understanding
how key discoveries were made and how these are applied in the real work. Class work includes brief writing assignments as well as a final research proposal and scientific presentation. </span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-family:"Calibri",sans-serif;color:#212121"> </span><span style="color:#212121"><o:p></o:p></span></p>
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<b><span style="font-family:"Calibri",sans-serif;color:#212121">7.38/7.83</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<b><span style="font-family:"Calibri",sans-serif;color:#212121">Design Principles of Biological Systems</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<b><span style="font-family:"Calibri",sans-serif;color:#212121">Faculty: Daniel Lev, Hari Wong</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<b><span style="font-family:"Calibri",sans-serif;color:#212121">T 1-2:30, F3:30-5</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-size:9.0pt;font-family:"Verdana",sans-serif;color:#333333;background:white">Introduces students to biological control mechanisms governing decision-making and tools to decipher, model, and perturb these mechanisms. Systems presented include
signal transduction, cell cycle control, developmental biology, and the immune system. These systems provide examples of feedback and feedforward control, oscillators, kinetic proofreading, spatial and temporal averaging, and pattern formation.</span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-family:"Calibri",sans-serif;color:#212121"> </span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-family:"Calibri",sans-serif;color:#212121"> </span><span style="color:#212121"><o:p></o:p></span></p>
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<b><span style="font-family:"Calibri",sans-serif;color:#212121">SPRING 2025</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<b><span style="font-family:"Calibri",sans-serif;color:#333333">7.C01</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<b><span style="font-family:"Calibri",sans-serif;color:#212121">Machine Learning in Molecular and Cellular Biology</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<b><span style="font-family:"Calibri",sans-serif;color:#212121">Faculty: </span></b><b><span style="font-family:"Calibri",sans-serif;color:#333333">C. Coley, J. Davis, E. Fraenkel, R. Gomez-Bombarelli</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<b><span style="font-family:"Calibri",sans-serif;color:#333333">Time TBD</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-size:9.0pt;font-family:"Verdana",sans-serif;color:#333333;background:white">Introduces machine learning as a tool to understand natural biological systems, with an evolving emphasis on problems in molecular and cellular biology that are being
actively advanced using machine learning. Students design, implement, and interpret machine learning approaches to aid in predicting protein structure, probing protein structure/function relationships, and imaging biological systems at scales ranging from
the atomic to cellular. Students taking graduate version complete an additional project-based assignment. Students cannot receive credit without simultaneous completion of 6.C01.</span><span style="font-size:9.0pt;font-family:"Verdana",sans-serif;color:#333333"><br>
<i>C. Coley, J. Davis, E. Fraenkel, R. Gomez-Bombarelli</i></span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-family:"Calibri",sans-serif;color:#212121"> </span><span style="color:#212121"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Calibri",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Calibri",sans-serif"><o:p> </o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Calibri",sans-serif;mso-ligatures:none">-- <o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Calibri",sans-serif;color:#212121;mso-ligatures:none">Joshua Stone</span><span style="font-size:12.0pt;font-family:"Calibri",sans-serif;color:#212121;mso-ligatures:none"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Calibri",sans-serif;color:#212121;mso-ligatures:none">Undergraduate Program</span><span style="font-size:12.0pt;font-family:"Calibri",sans-serif;color:#212121;mso-ligatures:none"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Calibri",sans-serif;color:#212121;mso-ligatures:none">Biology Education Office 68-120</span><span style="font-size:12.0pt;font-family:"Calibri",sans-serif;color:#212121;mso-ligatures:none"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Calibri",sans-serif;color:#212121;mso-ligatures:none">Massachusetts Institute of Technology</span><span style="font-size:12.0pt;font-family:"Calibri",sans-serif;color:#212121;mso-ligatures:none"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Calibri",sans-serif;color:#212121;mso-ligatures:none">31 Ames Street </span><span style="font-size:12.0pt;font-family:"Calibri",sans-serif;color:#212121;mso-ligatures:none"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Calibri",sans-serif;color:#212121;mso-ligatures:none">Cambridge, MA 02139</span><span style="font-size:12.0pt;font-family:"Calibri",sans-serif;color:#212121;mso-ligatures:none"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Calibri",sans-serif;color:#212121;mso-ligatures:none"><a href="mailto:stonej@mit.edu"><span style="color:#0563C1">stonej@mit.edu</span></a>
</span><span style="font-size:12.0pt;font-family:"Calibri",sans-serif;color:#212121;mso-ligatures:none"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Calibri",sans-serif;color:#212121;mso-ligatures:none">P: 617-253-4718
</span><span style="font-size:12.0pt;font-family:"Calibri",sans-serif;color:#212121;mso-ligatures:none"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Calibri",sans-serif;color:#212121;mso-ligatures:none">F: 617-258-9329<o:p></o:p></span></p>
<p class="MsoNormal"><i><span style="font-family:"Apple Chancery";color:#212121;mso-ligatures:none">Have a Blessed day.<o:p></o:p></span></i></p>
<p class="MsoNormal"><a href="https://lbgtq.mit.edu/you-are-welcome-here"><span style="font-size:12.0pt;font-family:"Calibri",sans-serif;color:#212121;text-decoration:none"><img border="0" width="300" height="192" style="width:3.125in;height:2.0in" id="Picture_x0020_1" src="cid:image001.jpg@01DAF890.13D42420" alt="signature_3375207027"></span></a><o:p></o:p></p>
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