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<p class="MsoNormal"><b><span style="font-size:12.0pt;color:black">From: </span></b><span style="font-size:12.0pt;color:black">"Denton Ii, William David" <WDENTONII@mgh.harvard.edu><br>
<b>Subject: </b>Job Opportunity: Rivera Lab Mass General<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:10.5pt;font-family:"-apple-system",serif">GENERAL SUMMARY/ OVERVIEW STATEMENT: <o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:10.5pt;font-family:"-apple-system",serif">The Rivera laboratory is part of the MGH Pathology Department and MGH Cancer Center and we are also affiliated with the Broad Institute. Our work is focused on using genomic
technologies to identify and characterize abnormal gene regulation pathways that drive cancer cells. Our studies involve the integration of biochemistry, cell biology and genome-wide profiling of chromatin and transcriptional states (such as ChIP-seq, ATAC-seq,
RNA-seq, Hi-ChIP and HiC). Using these approaches, our laboratory has uncovered gene regulation networks and new mechanisms of chromatin regulation in a variety of tumor types, including medulloblastoma (Boulay et al, Cancer Discovery 2017) and Ewing sarcoma
(Riggi et al, Cancer Cell 2014; Boulay et al, Cell 2017). Research technicians will join a collaborative group of scientists working on cutting edge research. <o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:10.5pt;font-family:"-apple-system",serif">PRINCIPAL DUTIES AND RESPONSIBILITIES: <o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:10.5pt;font-family:"-apple-system",serif">As members of the team, research technicians are expected to work closely with postdoctoral fellows and contribute experimentally to one or several research projects in the
laboratory. Contributions will include: setting up and performing experiments, assisting with hypothesis generation, experimental design and data interpretation. Common assays include western blotting, qPCR, cloning, RNA/DNA isolation, genomic assays (e.g.
ChIP-seq, RNA-seq), lentivirus production, general mammalian cell culture, mouse breeding and genotyping.<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:10.5pt;font-family:"-apple-system",serif"><a href="http://partners.taleo.net/careersection/ghc/jobdetail.ftl?job=3187478&tz=GMT-05:00&tzname=America/New_York" target="_blank">partners.taleo.net/careersection/ghc/jobdetail.ftl?job=3187478&tz=GMT-05:00&tzname=America/New_York</a><o:p></o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:8.5pt;font-family:"Times New Roman",serif">William David Denton II</span></b><span style="font-size:10.0pt;font-family:Helvetica">
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<p class="MsoNormal"><span style="font-size:8.5pt;font-family:"Times New Roman",serif">Research Technician</span><span style="font-size:10.0pt;font-family:Helvetica"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:8.5pt;font-family:"Times New Roman",serif">Molecular Pathology Unit</span><span style="font-size:10.0pt;font-family:Helvetica"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:8.5pt;font-family:"Times New Roman",serif">Massachusetts General Hospital/Harvard Medical School</span><span style="font-size:10.0pt;font-family:Helvetica"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:8.5pt;font-family:"Times New Roman",serif">Email: <a href="mailto:wdentonII@mgh.harvard.edu">wdentonII@mgh.harvard.edu</a></span><span style="font-size:10.0pt;font-family:Helvetica"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:8.5pt;font-family:"Times New Roman",serif">Phone: +1(270)933-7102</span><span style="font-size:10.0pt;font-family:Helvetica"><o:p></o:p></span></p>
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<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="font-size:10.0pt;font-family:Helvetica">The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent
to you in error and the e-mail contains patient information, please contact the Mass General Brigham Compliance HelpLine at
<a href="https://www.massgeneralbrigham.org/complianceline">https://www.massgeneralbrigham.org/complianceline</a> .<o:p></o:p></span></p>
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<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="font-size:10.0pt;font-family:Helvetica">Please note that this e-mail is not secure (encrypted). If you do not wish to continue communication over unencrypted e-mail,
please notify the sender of this message immediately. Continuing to send or respond to e-mail after receiving this message means you understand and accept this risk and wish to continue to communicate over unencrypted e-mail.
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