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<p class="MsoNormal"><b><span style="font-size:12.0pt;color:black">From: </span></b><span style="font-size:12.0pt;color:black">Chelsea Catania <cataniac@mit.edu><br>
<b>Subject: </b>Microbiome Club Seminar: Prof Neel Joshi on 2/24 at 12 PM<o:p></o:p></span></p>
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<span style="font-size:18.0pt;font-family:"Avenir Book";color:#77984C">MIT Microbiome Club </span><o:p></o:p></p>
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<span style="font-size:18.0pt;font-family:"Avenir Book";color:#77984C">Seminar Series</span><o:p></o:p></p>
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<img width="150" height="146" style="width:1.5625in;height:1.5208in" id="_x0031_6B7E9D8-A90D-4488-A00C-6C84C4547E6B" src="cid:image001.jpg@01D5E71D.FAECFA00"><o:p></o:p></p>
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<b><span style="font-size:24.0pt;font-family:"Avenir Book";color:#28916B">Prof. Neel Joshi </span></b><o:p></o:p></p>
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<i><span style="font-size:24.0pt;font-family:"Avenir Book";color:#28916B">Biologically fabricated materials from engineered microbes</span></i><o:p></o:p></p>
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<span style="font-size:18.0pt;font-family:"Avenir Book";color:#3A3E44">Monday, February 24th t at 12 pm in </span><a href="https://whereis.mit.edu/?go=56"><span style="font-size:18.0pt;font-family:"Avenir-Book",serif">MIT 56-614</span></a><o:p></o:p></p>
<p class="MsoNormal" align="center" style="text-align:center"><span style="font-size:24.0pt;font-family:"Avenir-Book",serif;color:#444444">Lunch will be provided. Please</span><span style="font-size:18.0pt;font-family:"Avenir-Book",serif"> </span><span style="font-size:18.0pt"><a href="https://www.eventbrite.com/e/microbiome-club-seminar-prof-neel-joshi-tickets-93830221719">RSVP</a></span><o:p></o:p></p>
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<b><span style="font-size:13.5pt;font-family:"Avenir-Book",serif;color:#444444;letter-spacing:.4pt">Abstract: </span></b><span style="font-size:13.5pt;font-family:"Avenir-Book",serif;color:#444444;letter-spacing:.4pt">The intersection between synthetic biology
and materials science is an underexplored area with great potential to positively affect our daily lives, with applications ranging from manufacturing to medicine. My group is interested in harnessing the biosynthetic potential of microbes, not only as factories
for the production of raw materials, but as fabrication plants that can orchestrate the assembly of complex functional materials. We call this approach “biologically fabricated materials”, a process whose goal is to genetically program microbes to assemble
materials from biomolecular building blocks without the need for time consuming and expensive purification protocols or specialized equipment. Accordingly, we have developed Biofilm Integrated Nanofiber Display (BIND), which relies on the biologically directed
assembly of biofilm matrix proteins of the curli system in <i>E. coli</i>. We demonstrate that bacterial cells can be programmed to synthesize a range of functional materials with straightforward genetic engineering techniques. The resulting materials are
highly customizable and easy to fabricate, and we are investigating their use for practical uses ranging from bioremediation to engineered therapeutic probiotics. Another project in the group focuses on interfacing yeast cells with light harvesting nanoparticles
to create inorganic-biohybrids with light-driven enhanced metabolic output. </span><span style="letter-spacing:.4pt"><o:p></o:p></span></p>
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<b><span style="font-size:11.5pt;font-family:"Avenir-Book",serif;color:#232323;letter-spacing:.4pt">Bio: </span></b><span style="font-size:11.5pt;font-family:"Avenir-Book",serif;color:#232323;letter-spacing:.4pt">Neel Joshi is an Associate Professor in the
Department of Chemistry and Chemical Biology at Northeastern University. He completed his PhD at UC Berkeley in the lab of Matt Francis and a postdoc at Boston University in the lab of Mark Grinstaff before starting his independent academic career at Harvard
University and then moving to Northeastern in January 2020. He is broadly interested in topics related to biologically inspired materials, protein engineering, self-assembly, and biointerfaces. His group works at the intersection of biomaterials science and
synthetic biology. Recent projects in the group have focused on repurposing bacterial biofilms and their matrix proteins for biotechnological and biomedical applications.</span><span style="letter-spacing:.4pt"><o:p></o:p></span></p>
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<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="font-family:"Avenir Book";color:black">______________________________ </span><span style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><i><span style="font-family:"Avenir Book";color:#16191F">The MIT Microbiome Club, part of the Center for Microbiome Informatics and Therapeutics, brings together inquisitive MIT
undergrads, grad researchers, postdocs, faculty, and clinicians in the emerging field of microbiome studies and microbiome-based medicine.<a href="https://www.facebook.com/MITmicrobiomeclub/"><span style="color:#16191F"> </span><span style="color:#386EFF">Learn
more on our Facebook page. </span></a>Or follow us on </span></i><span style="color:black"><a href="https://twitter.com/MITubiomeclub"><i><span style="font-family:"Avenir Book"">Twitter</span></i></a></span><i><span style="font-family:"Avenir Book";color:#16191F">. </span></i><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><b><span style="font-family:"Avenir-Book",serif;color:black">Chelsea Catania, Ph.D.</span></b><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Avenir-Book",serif;color:black">MIT Microbiome Club Publicity Chair</span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Avenir-Book",serif;color:black">Postdoctoral Associate</span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Avenir-Book",serif;color:black">Laboratory for Energy and Microsystems Innovation</span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Avenir-Book",serif;color:black">Department of Mechanical Engineering</span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Avenir-Book",serif;color:black">@<a href="https://twitter.com/MITubiomeclub">MITubiomeclub</a> </span><span style="color:black"><o:p></o:p></span></p>
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