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<p class="MsoNormal"><b><span style="font-size:12.0pt;color:black">From: </span></b><span style="font-size:12.0pt;color:black">Chelsea Catania <cataniac@mit.edu><br>
<b>Subject: </b>MIT Microbiome Club Seminar Wed, 10/16 @ 4PM<o:p></o:p></span></p>
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<span style="font-size:24.0pt;font-family:"Avenir Book";color:#77984C">MIT Microbiome Club Seminar</span><o:p></o:p></p>
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<span style="font-size:12.0pt"><img width="108" height="105" style="width:1.125in;height:1.0937in" id="C6D0E618-023A-479B-B60A-AE1E1D9E3E3F" src="cid:image001.jpg@01D58333.EA504EC0"><o:p></o:p></span></p>
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<b><span style="font-size:18.0pt;font-family:"Avenir Book";color:#28916B">Dr. Aspen Reese</span></b><o:p></o:p></p>
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<i><span style="font-size:18.0pt;font-family:"Avenir Book";color:#28916B">Domestication effects on the mammalian gut microbiota are </span></i><o:p></o:p></p>
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<i><span style="font-size:18.0pt;font-family:"Avenir Book";color:#28916B">mediated by dietary shifts</span></i><o:p></o:p></p>
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<span style="font-size:18.0pt;font-family:"Avenir Book";color:#3A3E44">Wednesday, May 14th at 4:00PM in </span><span style="font-size:18.0pt;font-family:Avenir-Book"><a href="https://whereis.mit.edu/?go=56">56-614</a> </span><o:p></o:p></p>
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<p class="MsoNormal" style="line-height:12.85pt"><span style="font-size:12.0pt;font-family:Avenir-Book">Please RSVP via <a href="https://www.eventbrite.com/e/microbiome-club-seminar-dr-aspen-reese-domestication-effects-on-the-mammalian-gut-microbiota-are-tickets-75689604645">Eventbrite</a>.</span><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<span style="font-size:12.0pt;font-family:Avenir-Book"> </span><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal" style="line-height:12.85pt"><span style="font-size:12.0pt;font-family:Avenir-Book">The gut microbiota provide crucial functions to their host, impacting diverse aspects of biology from metabolism and immunity to behavior. Thus, shifts in
the microbiota can be an important pathway by which animals respond to environmental change. Some microbial shifts can benefit the host, but others are likely to be costly. Domestication is an evolutionary process which resulted in substantial genetic and
ecological changes with potentially profound implications for the microbiota. The domestic microbiota are predicted to resemble that of modern industrialized human populations as the disruptions to historic host-microbe relationships were similar—including
diet shifts, changes in movement and density, antibiotic use, and altered breeding and birthing. Microbial changes may not have been exclusively negative, however, and microbial responses to domestication that enhanced host phenotypes valuable to humans may
even have been selected for. Drawing on comparative observational datasets and experiments in wild and domestic mice and canids, I have found that the domestic microbiota shows enhanced metabolism for domestic diets but may have lost traits relevant to host
immunity. Beyond illuminating the role of the microbiota in domestic animal evolution, these data have potential application in promoting health as domestic animals are the primary organisms for biomedical research and are important sources of zoonotic diseases.</span><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<span style="font-size:12.0pt;font-family:Avenir-Book"> </span><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal" style="line-height:12.85pt"><span style="font-size:12.0pt;font-family:Avenir-Book">Bio: Aspen Reese is a Junior Fellow at the Harvard Society of Fellows, where she studies the ecology and evolution of the gut microbiota. Before starting
at Harvard, she completed a BS in Biology at Yale University and a PhD in Ecology at Duke University. Beginning in 2020, she will be an Assistant Professor in the Ecology, Behavior, and Evolution Department at University of California, San Diego.</span><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="font-family:"Avenir Book";color:black">______________________________ </span><span style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><i><span style="font-family:"Avenir Book";color:#16191F">The MIT Microbiome Club, part of the Center for Microbiome Informatics and Therapeutics, brings together inquisitive MIT
undergrads, grad researchers, postdocs, faculty, and clinicians in the emerging field of microbiome studies and microbiome-based medicine.<a href="https://www.facebook.com/MITmicrobiomeclub/"><span style="color:#16191F"> </span><span style="color:#386EFF">Learn
more on our Facebook page. </span></a>Or follow us on </span></i><span style="color:black"><a href="https://twitter.com/MITubiomeclub"><i><span style="font-family:"Avenir Book"">Twitter</span></i></a></span><i><span style="font-family:"Avenir Book";color:#16191F">. </span></i><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><b><span style="font-family:Avenir-Book;color:black">Chelsea Catania, Ph.D.</span></b><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:Avenir-Book;color:black">MIT Microbiome Club Seminar Chair</span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:Avenir-Book;color:black">Postdoctoral Associate</span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:Avenir-Book;color:black">Laboratory for Energy and Microsystems Innovation</span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:Avenir-Book;color:black">Department of Mechanical Engineering</span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:Avenir-Book;color:black">@<a href="https://twitter.com/MITubiomeclub">MITubiomeclub</a> </span><span style="color:black"><o:p></o:p></span></p>
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