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<p class="MsoNormal" align="center" style="text-align:center"><b class=""><span style="font-size:18.0pt;mso-bidi-font-size:12.0pt;font-family:
"Arial",sans-serif" class="">LEARN ADVANCED TOPICS IN BIOTECHNOLOGY AND DEVELOP IMPORTANT TEACHING SKILLS<o:p class=""></o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b class=""><span style="font-size:14.0pt;font-family:"Arial",sans-serif" class=""> </span></b></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif" class="">For the past five years Professors Jianzhu Chen and Harvey Lodish have taught an advanced undergraduate seminar course,
</span><span style="font-size: 14pt; font-family: Arial, sans-serif;" class="">7.371,
</span><b class=""><span style="font-size:14.0pt;font-family:"Arial",sans-serif" class="">Biological and Engineering Principles Underlying Novel Biotherapeutics</span></b><span style="font-size:14.0pt;font-family:"Arial",sans-serif" class="">, to a small group
of 3<sup class="">rd</sup> and 4<sup class="">th</sup> year undergraduate Biology and Biological Engineering students. We are looking for a senior/graduate student/postdoc who can assist us with this seminar course this coming fall term and serve as a third
course instructor, in exchange to learn advanced topics in biotechnology and develop important teaching skills.
<o:p class=""></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif" class=""> </span></p>
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include lectures, but mainly focus on discussion of current research and clinical papers. Class meets Mondays and Wednesdays from 3:00 to 5:00.
<o:p class=""></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif" class=""> </span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif" class="">Topics covered include:<o:p class=""></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif" class=""> </span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;mso-bidi-font-size:14.0pt;
font-family:"Arial",sans-serif" class="">• Production of recombinant proteins and antibodies<o:p class=""></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;mso-bidi-font-size:14.0pt;
font-family:"Arial",sans-serif" class="">•
</span><span style="font-size:11.0pt;
mso-bidi-font-size:14.0pt;font-family:"Arial",sans-serif;mso-bidi-language:
EN-US;mso-bidi-font-style:italic" class="">Antibody therapeutics and monoclonal - drug conjugates</span><span style="font-size:11.0pt;mso-bidi-font-size:14.0pt;
font-family:"Arial",sans-serif" class=""><o:p class=""></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;mso-bidi-font-size:14.0pt;
font-family:"Arial",sans-serif" class="">• G</span><span style="font-size:11.0pt;
mso-bidi-font-size:14.0pt;font-family:"Arial",sans-serif;mso-bidi-language:
EN-US" class="">ene
therapies using retrovirus and AAV vectors<o:p class=""></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;mso-bidi-font-size:14.0pt;
font-family:"Arial",sans-serif;mso-bidi-language:EN-US" class="">• Oligonucleotides as therapeutics<o:p class=""></o:p></span></p>
<p class="MsoNormal"><span style="font-size: 11pt; font-family: Arial, sans-serif;" class="">• Cancer immunotherapies, including checkpoint inhibitors<o:p class=""></o:p></span></p>
<p class="MsoNormal"><span style="font-size: 11pt; font-family: Arial, sans-serif;" class="">• Manipulating immune effector cells<o:p class=""></o:p></span></p>
<p class="MsoNormal"><span style="font-size: 11pt; font-family: Arial, sans-serif;" class="">• CAR-T cells<o:p class=""></o:p></span></p>
<p class="MsoNormal"><span style="font-size: 11pt; font-family: Arial, sans-serif;" class="">• Cancer vaccines</span><span style="font-size:11.0pt;mso-bidi-font-size:
14.0pt;font-family:"Arial",sans-serif;mso-bidi-language:EN-US" class=""><o:p class=""></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;mso-bidi-font-size:14.0pt;
font-family:"Arial",sans-serif;mso-bidi-language:EN-US" class="">• Generation of insulin- producing cells from ES and iPS stem cells.
<o:p class=""></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif;
mso-bidi-language:EN-US;mso-bidi-font-style:italic" class=""> </span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif;
mso-bidi-language:EN-US;mso-bidi-font-style:italic" class="">Responsibilities include monitoring class participation by the students, leading one or two classes on topics of
your choice, and working with students as they formulate their term paper – the latter either an NIH- format grant application or a business plan.<o:p class=""></o:p></span></p>
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mso-bidi-language:EN-US;mso-bidi-font-style:italic" class=""> </span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif;
mso-bidi-language:EN-US;mso-bidi-font-style:italic" class="">If interested contact either
<o:p class=""></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif;
mso-bidi-language:EN-US;mso-bidi-font-style:italic" class="">Professor Jianzhu Chen
<span class="MsoHyperlink"><a href="mailto:jchen@mit.edu" class="">jchen@mit.edu</a></span>; 258-6173<o:p class=""></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif;
mso-bidi-language:EN-US;mso-bidi-font-style:italic" class="">Professor Harvey Lodish
<span class="MsoHyperlink"><a href="mailto:lodish@wi.mit.edu" class="">lodish@wi.mit.edu</a></span>; 258- 5216</span><span style="font-size:14.0pt;font-family:"Arial",sans-serif" class=""><o:p class=""></o:p></span></p>
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