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<p class="MsoNormal"><b><span style="font-family:"Helvetica Neue"">From: </span></b><span style="font-family:"Helvetica Neue"">"Reeves, Melissa" <<a href="mailto:Melissa.Reeves@ucsf.edu">Melissa.Reeves@ucsf.edu</a>></span><o:p></o:p></p>
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<p class="MsoNormal"><b><span style="font-family:"Helvetica Neue"">Subject: Open position in tumor immunology - Reeves Lab UCSF</span></b><o:p></o:p></p>
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<p class="MsoNormal"><b><span style="font-family:"Helvetica Neue"">Date: </span></b><span style="font-family:"Helvetica Neue"">March 28, 2019 at 3:32:27 PM EDT</span><o:p></o:p></p>
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<p class="MsoNormal" style="background:white">My lab at UCSF is currently hiring a research assistant to start summer 2019. I was wondering if you would mind forwarding the information below to any MIT students who might be interested? The position is open
to anyone who will have graduated (B.S./B.A.) by this summer.<span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white">Thanks,<span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white">Melissa Reeves<span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white">***<span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white">The Reeves Lab at UCSF studies tumor heterogeneity and its influence on the anti-tumor immune response. We have developed a unique model system to study heterogeneity using the “Confetti” mouse—a mouse containing
a cassette which, when activated, permanently, randomly labels cells one of four colors. This permits us to study heterogeneity by labeling multiple clones in a tumor with different colors and following them side-by-side over time. We are currently hiring
a tech/junior specialist, who will specifically be involved studying the impact of tumor composition on the immune response. We have found that some tumor cells, when allowed to form a tumor on their own, are highly infiltrated by T cells; while others are
an “immune desert” with few infiltrating T cells. We now plan to use this system to determine by what mechanism these tumor cells dictate the level of infiltrating T cells, as well as how a heterogeneous tumor comprised of both types of tumor cells would behave.<span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white">Learn more about our research: <a href="https://www.reeveslab.com/"><span style="color:#954F72">https://www.reeveslab.com/</span></a><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white">For more information and to apply: <a href="https://aprecruit.ucsf.edu/JPF02430"><span style="color:#954F72">https://aprecruit.ucsf.edu/JPF02430</span></a><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white">--<span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white"><i>Melissa Reeves, PhD</i><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white"><i>Sandler Faculty Fellow</i><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white"><i>Department of Microbiology & Immunology</i><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white"><i>University of California, San Francisco</i><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white"><i>513 Parnassus Ave, HSE-301</i><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white"><i>San Francisco, CA 94143 Box 0519</i><span style="font-size:12.0pt"><o:p></o:p></span></p>
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