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<p class="MsoNormal">Begin forwarded message:<o:p></o:p></p>
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<p class="MsoNormal"><b>From: </b>Sarah J Smith <<a href="mailto:ssmith1@mit.edu">ssmith1@mit.edu</a>><o:p></o:p></p>
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<p class="MsoNormal"><b>Subject: Spring Subject Offering :: 1.S993 Genomics and Evolution of Infectious Diseases</b><o:p></o:p></p>
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<p class="MsoNormal"><b>Date: </b>January 23, 2019 at 10:59:41 AM EST<o:p></o:p></p>
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<p class="MsoNormal"><span style="font-family:"Calibri Light",sans-serif">Could you please share this spring subject offering with your students?</span><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:12.0pt;font-family:"Calibri Light",sans-serif">1.S993 Genomics and Evolution of Infectious Diseases</span></b><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Calibri Light",sans-serif">Pre-reqs: BIOLOGY (GIR) and 1.000 or 6.0001, or permission of instructor</span><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Calibri Light",sans-serif">3-0-9</span><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Calibri Light",sans-serif">Introduces principles of evolution and evolutionary inference, with an emphasis on evolution in action, using a combination of lectures, discussion of primary literature, and computational
assignments. Emphasizes the insights that can be obtained from studying evolution in action, using examples from infectious disease, environmental engineering, drug resistance, and laboratory experiments. Covers key concepts and tools including the speed of
evolution, clonal interference, mechanisms of genetic variation, phylogenetic inference, detection of adaptation, epistasis, coevolution, strategies to impede drug resistance, and outbreak detection. Problem sets provide experience working with real world
data.</span><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Calibri Light",sans-serif">Lectures: MW 1-2:30 pm in 1-371</span><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Calibri Light",sans-serif">Additional information about this subject can be found<span class="xapple-converted-space"> </span><a href="https://bit.ly/2VKVg3A"><span style="color:#954F72">here</span></a>.</span><span style="font-size:12.0pt"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Calibri Light",sans-serif">Instructor: T. Lieberman</span><span style="font-size:12.0pt"><o:p></o:p></span></p>
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